Continuous Renal Replacement Therapy in Acute Renal Failure

  • Paul Ellis Marik


Continuous renal replacement therapies (CRRTs) have been developed to enable the critically ill patient with acute renal failure to be treated more effectively. Acute renal failure in the critically ill patient almost always develops in the setting of shock, sepsis, major surgery, and/or major trauma, and is invariably associated with multiorgan dysfunction and/or failure. In addition, these patients usually have hemodynamic and respiratory abnormalities that make conventional intermittent hemodialysis both technically difficult and fraught with many complications. The patient’s fluid, electrolyte, and acid-base status fluctuate widely within a 24-hour period; intermittent dialysis is not suited to these changing circumstances.


Acute Renal Failure Renal Replacement Therapy Continuous Renal Replacement Therapy Dialysate Flow Intermittent Hemodialysis 
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Copyright information

© Springer-Verlag New York, Inc. 2001

Authors and Affiliations

  • Paul Ellis Marik
    • 1
  1. 1.Critical Care MedicineMercy Hospital of PittsburghPittsburghUSA

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