Abstract
Rules of the Game
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Sodium balance determines volume status.
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Water balance determines tonicity, i.e., Na+ concentration.
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Volume overload = increased total body sodium (regardless of serum sodium concentration)
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Euvolemia = normal total body sodium (regardless of serum sodium concentration)
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Volume depletion - decreased total body sodium (regardless of serum sodium concentration)
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Hyponatremia = relative water excess
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Hypernatremia = relative water deficit
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Selected References
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Marik, P.E. (2001). Electrolyte Disturbances. In: Handbook of Evidence-Based Critical Care. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86943-3_30
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DOI: https://doi.org/10.1007/978-3-642-86943-3_30
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