Sweden: Neuroleptic Treatment Strategies and Practical Problems During Drugs Withdrawal

  • B. Wistedt
Conference paper


About 90% of schizophrenics are mainly outpatients 5–15 years after onset, but they often relapse and are taken care of for very short periods in the psychiatric clinics. This increased “turnover” of patients creates special problems, but the possibility of permanent recovery from a schizophrenic illness is probably greater today than it was half a century ago, when about 50% were chronically hospitalized. The risk, however, of being permanently incapacitated in some way, unable to work, is still 50% or more even for young schizophrenic patients (Wistedt 1981a).


Schizophrenic Patient Drug Withdrawal Haloperidol Decanoate Depot Preparation Chronic Schizophrenic 
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  1. Bergmark T, Wistedt B (1989) CBS-R, a new scale for burden on relatives, and effects of education (Poster). 8th World Congress of Psychiatry, 13–19 Oct, AthensGoogle Scholar
  2. Dencker S J, Malm U (1986) Schizophrenia relapse after drug withdrawal is predictable. Acta Psychiatr Scand 3(73):181–185CrossRefGoogle Scholar
  3. Kane JM (1983) Problems of compliance in the outpatient treatment of schizophrenia. J Clin Psychiatry 1:3–6Google Scholar
  4. Mantonakis J, Markidis M, Kontaxakis V, Liakos A (1985) A scale for detection of negative attitude towards medication among relatives of schizophrenic patients. Acta Psychiatr Scand 2:186–189CrossRefGoogle Scholar
  5. Palmstierna T, Wistedt B (1987) Absence of acquired tolerance to neuroleptics in schizophrenic patients. Am J Psychiatry 144:1084–1085PubMedGoogle Scholar
  6. Rifkin A (1987) A historical review of the adverse reactions to neuroleptic agents. J Clin Psychiatry [Suppl 48] 3:6Google Scholar
  7. Van Putten T (1974) Why do schizophrenic patients refuse to take their drugs? Gen Psychiatry 31:67–72CrossRefGoogle Scholar
  8. Wistedt B (1981a) Schizophrenia, a chronic disease. Acta Psychiatr Scand 63 [Suppl 291]:9–19CrossRefGoogle Scholar
  9. Wistedt B (1981 b) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatr Scand 64:65–84PubMedCrossRefGoogle Scholar
  10. Wistedt B (1983) Effect of neuroleptic withdrawal during the maintenance treatment of chronic schizophrenics. Special Symposium of the 7th World Congress of Psychiatry, ViennaGoogle Scholar
  11. Wistedt B, et al. (1981) Slow decline of plasma drug and prolactin levels following discontinuation of chronic treatment with depot neuroleptic patients. Lancet 1:1163PubMedCrossRefGoogle Scholar
  12. Wistedt B, et al. (1982) A depot neuroleptic withdrawal study. Psychopharmacology (Berlin) 78:301–304 ’CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • B. Wistedt

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