Human Germinal Centers Lymph Nodes Responses to Leukemogenic Viruses in vitro

  • L. Jankay
  • P. T. Jankay
  • S. Liu
  • B. Samp


The responses of the lymphoid system of different species of animals to various antigens are well documented. In our experiments we made an approach to study the responses of human lymph nodes and human peripheral heparinized whole blood, to the presence of animal leukemogenic virus (Rauscher)2 in vitro. This study revealed that human lymph node and whole blood respond to the Rauscher leukemia virus with a pattern of formation of large basophilic blast-like cells demonstrating mitotic activity, large mononuclear cells with intranuclear inclusion bodies and plasma cells.


Chronic Lymphocytic Leukemia Tissue Culture Method Lymphoid System Virus Addition Human Lymph Node 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1967

Authors and Affiliations

  • L. Jankay
  • P. T. Jankay
  • S. Liu
  • B. Samp
    • 1
    • 2
  1. 1.Harbor General HospitalTorranceUSA
  2. 2.Studebaker HospitalNorwalkUSA

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