Human Germinal Centers Lymph Nodes Responses to Leukemogenic Viruses in vitro

Jankay, L.; Jankay, P. T.; Liu, S.; Samp, B.

doi:10.1007/978-3-642-86837-5_53

L. Jankay,
P. T. Jankay,
S. Liu &
…
B. Samp^5,6

45 Accesses

Abstract

The responses of the lymphoid system of different species of animals to various antigens are well documented. In our experiments we made an approach to study the responses of human lymph nodes and human peripheral heparinized whole blood, to the presence of animal leukemogenic virus (Rauscher)² in vitro. This study revealed that human lymph node and whole blood respond to the Rauscher leukemia virus with a pattern of formation of large basophilic blast-like cells demonstrating mitotic activity, large mononuclear cells with intranuclear inclusion bodies and plasma cells.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Chapter: USD 29.95; Price excludes VAT (USA)

eBook: USD 84.99; Price excludes VAT (USA)

Softcover Book: USD 109.99; Price excludes VAT (USA)

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

References

André-Schwartz, J.: The morphologic responses of the lymphoid system to homografts. III. Electron microscopy study. Blood 24, 113–133 (1964).
PubMed Google Scholar
Bain, B., and L. Lowenstein: Genetic studies on the mixed leucocyte reactions. Science 145, 1315–1316 (1964).
Article PubMed CAS Google Scholar
Gross, L.: Viral etiology of leukemia and lymphomas. Blood 25, 377–381 (1965).
PubMed CAS Google Scholar
Jankay, L.: 9th Congress of the European Society of Hematology. Sangre 9, 199–204 (1964).
Google Scholar
Jankay, L. and L. J. Cole: Research and development technical report. USNRDL-TR-S-Roll 0101, 1960.
Google Scholar
Jankay, L., and B. Kurnick: Cultivation of human bone marrow and cancer cell in autologous-heparinized whole blood. Blood 20, 104 (1962) (Abstract).
Google Scholar
Oppenheim, J. J., J. Whang, and E. Frei: III. Immunologic and cytogenetic studies of chronic lymphocytic leukemia cells. Blood 26, 121–132 (1965).
PubMed CAS Google Scholar

Download references

Author information

Authors and Affiliations

Harbor General Hospital, Torrance, Calif., USA
B. Samp
Studebaker Hospital, Norwalk, Calif., USA
B. Samp

Authors

L. Jankay
View author publications
You can also search for this author in PubMed Google Scholar
P. T. Jankay
View author publications
You can also search for this author in PubMed Google Scholar
S. Liu
View author publications
You can also search for this author in PubMed Google Scholar
B. Samp
View author publications
You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

Institute of Pathology, University of Bern, Switzerland
H. Cottier & R. Schindler &
Swiss Institute for Experimental Cancer Research, Lausanne, Switzerland
N. Odartchenko & R. Schindler &
Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA
C. C. Congdon

Rights and permissions

Reprints and permissions

Copyright information

About this chapter

Cite this chapter

Jankay, L., Jankay, P.T., Liu, S., Samp, B. (1967). Human Germinal Centers Lymph Nodes Responses to Leukemogenic Viruses in vitro. In: Cottier, H., Odartchenko, N., Schindler, R., Congdon, C.C. (eds) Germinal Centers in Immune Responses. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86837-5_53

Download citation

DOI: https://doi.org/10.1007/978-3-642-86837-5_53
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-86839-9
Online ISBN: 978-3-642-86837-5
eBook Packages: Springer Book Archive

Publish with us

Policies and ethics