Summary
Low-back pain is the most frequent and, usually, first symptom of fibromyalgia (FM). To decide if low-back pain in FM is caused by structural or static pathologic changes of the spine, we compared lumbar column x-rays of 47 female patients with x-rays of 45 age- and sex-matched controls. The x-rays of FM showed significantly more frequent static changes. Structural changes were also found more frequently in FM than in controls (especially osteochondrosis and pseudospondylolisthesis). Osteoarthritis, however, was seen in both collectives without any difference. The radiologically visible changes in lumbar spine could be one of many factors in the development of FM, although these findings are not of benefit for diagnosis and prognosis of this disease in the individual case. Most rheumatologists take pathological laboratory values for excluding FM. Nevertheless, it is assumed that thyroidal hormones, serotonin, and immunological parameters differ from healthy individuals. FM data from 98 patients were analyzed according to an extensive spectrum of laboratory parameters, and compared with the literature. Except for hyaluronic acid, only a few values were (often borderline) pathological. Summarizing pathological laboratory values plus diagnosis, FM has to be followed by differential diagnostic considerations. At present, there is no test which can confirm the diagnosis of FM.
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© 1991 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt
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Brückle, W. (1991). Röntgen- und Laborbefunde bei der generalisierten Tendomyopathie. In: Müller, W. (eds) Generalisierte Tendomyopathie (Fibromyalgie). Steinkopff. https://doi.org/10.1007/978-3-642-86812-2_17
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DOI: https://doi.org/10.1007/978-3-642-86812-2_17
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