Abstract

Only the amino acid sequence of a polypeptide chain defines its function. A polypeptide chain having a certain amino acid sequence serves as a subunit of immunoglobulin, while another polypeptide chain having a different amino acid sequence functions as a subunit of an enzyme, such as lactate dehydrogenase. It then follows that a change in the amino acid sequence of a polypeptide chain can deprive that polypeptide chain from the performance of its assigned function.

Keywords

Codon Cysteine Serine Pyruvate Glutamine 

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Copyright information

© Springer Science+Business Media New York 1970

Authors and Affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of BiologyCity of Hope Medical CenterDuarteUSA

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