Only the amino acid sequence of a polypeptide chain defines its function. A polypeptide chain having a certain amino acid sequence serves as a subunit of immunoglobulin, while another polypeptide chain having a different amino acid sequence functions as a subunit of an enzyme, such as lactate dehydrogenase. It then follows that a change in the amino acid sequence of a polypeptide chain can deprive that polypeptide chain from the performance of its assigned function.


Natural Selection Polypeptide Chain Disulfide Bridge Peptide Chain Heme Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1970

Authors and Affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of BiologyCity of Hope Medical CenterDuarteUSA

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