Deranged Fasting Motor Activity in the Duodenum and Proximal Small Intestine in Patients with Reflux Esophagitis
Gastroesophageal reflux (GER) is associated with esophageal motor disorders, reduced lower esophageal sphincter (LES) pressure, and delayed gastric emptying. Even with a normal resting LES pressure GER may occur due to transient relaxation of the sphincter after gastric distention (Holloway et al. 1985). Taken together, this indicates that GER might be a manifestation of a general smooth muscle disorder rather than just a disease of the LES.
KeywordsGastric Emptying Lower Esophageal Sphincter Reflux Esophagitis Lower Esophageal Sphincter Pressure Activity Front
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