Radionuclide Evaluation of Pharyngeal Emptying Before and After Cricopharyngeal Myotomy in Patients with Oculopharyngeal Muscular Dystrophy

  • R. Taillefer
  • G. Beauchamp
  • A. Duranceau
Conference paper


Oculopharyngeal muscular dystrophy (OMD) is a genetic condition transmitted with an autosomal dominant mode. It is characterized by a bilateral symmetrical ptosis with progressive oropharyngeal dysphagia occurring late in life (Duranceau et al. 1983). Motility studies have revealed an impaired pharyngeal function with weak and slow contractions. The unrelaxed or incompletely relaxed upper esophageal sphincter (UES) makes it a functional obstruction against the powerless pharynx. The goal of the treatment is to facilitate the passage of food from the pharynx to the cervical esophagus, across the UES. No medication provides significant help for that purpose and dilatation does not result in satisfactory long-term improvement (Duranceau et al. 1978). Cricopharyngeal myotomy remains the best approach to enhance the pharyngeal clearance of a food bolus (Peterman et al. 1964).


Oropharyngeal Dysphagia Pyriform Sinus Autosomal Dominant Mode Liquid Bolus Cricopharyngeal Myotomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Duranceau AC, Letendre J, Clermont R (1978) Oropharyngeal dysphagia in patients with oculopharyngeal muscular dystrophy. Can J Surg 21:326–329PubMedGoogle Scholar
  2. 2.
    Duranceau AC, Beauchamp G, Jamieson CG (1983) Oropharyngeal dysphagia and oculopharyngeal muscular dystrophy. Surg Clin North Am 63:825–832PubMedGoogle Scholar
  3. 3.
    Gross R, Johnson LF, Kaminski RJ (1979) Esophageal emptying in achalasia quantitated by a radioisotope technique. Dig Dis Sei 24:945–949CrossRefGoogle Scholar
  4. 4.
    Kazem I (1972) A new scintigraphic technique for the study of the esophagus. AJR 115:681–688Google Scholar
  5. 5.
    McCallum RW (1982) Radionuclide scanning in esophageal disease. J Clin Gastroenterol 4:67–70PubMedCrossRefGoogle Scholar
  6. 6.
    Peterman AF, Lillington GA, Jamplis RW (1964) Progressive muscular dystrophy with ptosis and dysphagia. Arch Neurol 10:38–11PubMedCrossRefGoogle Scholar
  7. 7.
    Rozen P, Gelfond M, Zaltzman S (1982) Dynamic, diagnostic, and pharmacological radionuclide studies of the esophagus in achalasia. Radiology 144:587–590PubMedGoogle Scholar
  8. 8.
    Taillefer R, Beauchamp G, Duranceau AC (1986) Nuclear medicine and esophageal surgery. Clin Nucl Med 11:445–460PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • R. Taillefer
    • 1
  • G. Beauchamp
    • 1
  • A. Duranceau
    • 1
  1. 1.Hôpital Hôtel-Dieu de MontréalUniversité de MontréalMontréalCanada

Personalised recommendations