Radionuclide Evaluation of Pharyngeal Emptying Before and After Cricopharyngeal Myotomy in Patients with Oculopharyngeal Muscular Dystrophy
Oculopharyngeal muscular dystrophy (OMD) is a genetic condition transmitted with an autosomal dominant mode. It is characterized by a bilateral symmetrical ptosis with progressive oropharyngeal dysphagia occurring late in life (Duranceau et al. 1983). Motility studies have revealed an impaired pharyngeal function with weak and slow contractions. The unrelaxed or incompletely relaxed upper esophageal sphincter (UES) makes it a functional obstruction against the powerless pharynx. The goal of the treatment is to facilitate the passage of food from the pharynx to the cervical esophagus, across the UES. No medication provides significant help for that purpose and dilatation does not result in satisfactory long-term improvement (Duranceau et al. 1978). Cricopharyngeal myotomy remains the best approach to enhance the pharyngeal clearance of a food bolus (Peterman et al. 1964).
KeywordsRadionuclide Straw Achalasia
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- 4.Kazem I (1972) A new scintigraphic technique for the study of the esophagus. AJR 115:681–688Google Scholar