Abstract
Gastro-oesophageal reflux (GOR) most commonly occurs postprandially especially during activities associated with increases in intra-abdominal pressure which may provoke reflux in susceptible subjects. Inflation of a gastric balloon, in increments up to 750 ml, significantly increases the frequency of transient lower oesophageal sphincter (LOS) relaxations in both normal subjects and patients with GOR [1]. These authors conclude that meal-induced gastric distension provokes LOS relaxations so contributing to postprandial reflux. We have developed a short-term acid reflux provocation test (ARPT) for diagnostic purposes.
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References
Holloway RH, Hongo M, Berger K, McCallum RW (1984) Gastric distension: a mechanism for postprandial gastro-esophageal reflux. Gastroenterology 86(5/2):1115
Branicki FJ, Evans DF, Ogilvie AL, Atkinson M, Hardcastle JD (1982) Ambulatory monitoring of oesophageal pH in reflux oesophagitis using a portable radiotelemetry system. Gut 23(11):992–998
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© 1988 Springer-Verlag
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Branicki, F.J., Evans, D.F., Jones, J.A., Atkinson, M., Hardcastle, J.D. (1988). A Short-Term Radiotelemetric Provocation Test for the Diagnosis of Gastroesophageal Reflux Disease. In: Siewert, J.R., Hölscher, A.H. (eds) Diseases of the Esophagus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86432-2_177
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DOI: https://doi.org/10.1007/978-3-642-86432-2_177
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-86434-6
Online ISBN: 978-3-642-86432-2
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