The Clinical Features and Biological Behavior of Adenocarcinoma of the Esophagus Complicating Barrett’s Esophagus

  • E. Achkar
  • W. D. Carey
  • G. Hall
  • R. Revta
Conference paper

Abstract

The association of Barrett’s esophagus and adenocarcinoma is well established. The prevalence of adenocarcinoma, based on surgical and autopsy series, has been found to be as high as 10%. However, the incidence of malignancy, defined as the occurrence of adenocarcinoma developing in a group of patients with Barrett’s esophagus followed over a long period, appears to be much less significant. The aims of the present study were (1) to compare the presenting symptoms of patients with adenocarcinoma in Barrett’s esophagus with patients with Barrett’s alone, (2) to determine the frequency of adenocarcinoma after Barrett’s esophagus is discovered, (3) to determine the outcome of esophageal cancer complicating Barrett’s esophagus, and (4) to estimate the probable cost of the surveillance program for adenocarcinoma.

Keywords

Adenocarcinoma Lost Noma Esophagitis 

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References

  1. 1.
    Spechler SJ, Robbins AH, Rubins HB et al. (1984) Adenocarcinoma and Barrett’s esophagus: an overrated risk? Gastroenterology 87:927–933PubMedGoogle Scholar
  2. 2.
    Rosenberg JV, Budev H, Edwards RC et al. (1985) Analysis of adenocarcinoma in Barrett’s esophagus utilizing a staging system. Cancer 55:1353–1360PubMedCrossRefGoogle Scholar
  3. 3.
    Haggitt RC, Dean PJ (1985) Adenocarcinoma in Barrett’s epithelium. In: Spechler SJ, Goyal RK (eds) Barrett’s esophagus: pathophysiology, diagnosis, and management. Elsevier, New York, pp 153–166Google Scholar
  4. 4.
    Cameron AJ, Ott BJ, Payne WS (1985) The incidence of adenocarcinoma in columnar-lined (Barrett’s) esophagus. N Engl J Med 313:857–859PubMedCrossRefGoogle Scholar
  5. 5.
    Sprung DJ, Ellis FH Jr, Gibb SP (1984) Incidence of adenocarcinoma in Barrett’s esophagus. Am J Gastroenterol 79:817 (abstract)Google Scholar
  6. 6.
    Spechler SJ, Goyal RK (1985) Barrett’s esophagus. N Engl J Med 315:362–369CrossRefGoogle Scholar
  7. 7.
    Riddell RH (1985) Dysplasia and regression in Barrett’s epithelium. In: Spechler SJ, Goyal RK (eds) Barrett’s esophagus: pathophysiology, diagnosis, and management. Elsevier, New York, pp 143:152Google Scholar
  8. 8.
    Reid BJ, Haggitt RC, Rubin CE et al. (1985) Criteria for dysplasia in Barrett’s esophagus: a cooperative consensus study. Gastroenterology 88:1552 (abstract)Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • E. Achkar
    • 1
  • W. D. Carey
    • 1
  • G. Hall
    • 1
  • R. Revta
    • 1
  1. 1.Department of GastroenterologyCleveland Clinic FoundationClevelandUSA

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