The Clinical Features and Biological Behavior of Adenocarcinoma of the Esophagus Complicating Barrett’s Esophagus
The association of Barrett’s esophagus and adenocarcinoma is well established. The prevalence of adenocarcinoma, based on surgical and autopsy series, has been found to be as high as 10%. However, the incidence of malignancy, defined as the occurrence of adenocarcinoma developing in a group of patients with Barrett’s esophagus followed over a long period, appears to be much less significant. The aims of the present study were (1) to compare the presenting symptoms of patients with adenocarcinoma in Barrett’s esophagus with patients with Barrett’s alone, (2) to determine the frequency of adenocarcinoma after Barrett’s esophagus is discovered, (3) to determine the outcome of esophageal cancer complicating Barrett’s esophagus, and (4) to estimate the probable cost of the surveillance program for adenocarcinoma.
KeywordsEsophageal Cancer Surveillance Program Probable Cost Increase Cure Rate Peptic Esophagitis
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