Skip to main content

Histology and Ultrastructure of Normal and Cryptorchid Testes

  • Chapter
Cryptorchidism

Abstract

Immediately after birth, the seminiferous tubule is composed of gonocytes, spermatogonia and Sertoli cells. The gonocytes or primitive repro ductive cells are located mainly in the centre of the tubule and show a tendency to move towards the basement membrane. Two different types of gonocytes can be distinguished (Fig. 1, Chap. 3). When the gonocyte comes into contact with the basement membrane, it changes into a fetal spermatogonium, the largest cell in the infant seminiferous tubule (Fig. 1, Chap. 3). The most common cell in the seminiferous tubule in the 1st year is the Sertoli cell, an oval or polarized cell which, by definition, is always in contact with the basement membrane (Figs. 1, 2, 3a). It is a small cell (410 µ3) fulfilling, in addition to phagocytizing, hormone-producing, and nutritive functions, a supporting role (Figs. 1, 2, 3a).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Hadžiselimovi F (1977) Cryptorchidism. Adv Anat Embryol Cell Biol 53/3

    Google Scholar 

  2. Palmer JF (1837) The works of John Hunter. F.R.S. vol 4, London, Longman

    Google Scholar 

  3. Bland-Sutton J (1910) The values of the undescended testis. Practitioner 84:19

    Google Scholar 

  4. Charny CW, Wolgin W (1957) Cryptorchidism. Paul B. Hoeber, New York

    Google Scholar 

  5. Cooper ERA (1929) The histology of the retained testis in the human subject at different ages and its compari son with the scrotal testis. J Anat 64:5–27

    PubMed  CAS  Google Scholar 

  6. Kleinteich B, Hadžiselimovi F, Hesse V, Schreiber G (1979) Kongenitale Hodendystopien. VEB Georg Thieme, Leipzig

    Google Scholar 

  7. Hadžiselimovi F (1981) Pathogenesis of cryptorchidism. In: Kogan SJ, Hafez ESE (eds) Pediatric andrology. Martinus Nijhoff, Den Hague

    Google Scholar 

  8. Bar-Maor JA, Nissan S, Lernau DZ, Oren M, Levy E (1979) Orchidopexy in cryptorchidism assessed by clinical, histologic and sperm examinations. Surg Gynecol Obstet 148:855–859

    PubMed  CAS  Google Scholar 

  9. Sohval RA (1954) Histopathology of Cryptorchidism. Am JMed 16:346–362

    CAS  Google Scholar 

  10. Hösli PO (1971) Zur Problematik der Behandlung des Kryptorchismus. Aktuel Urol 2:107–120

    Google Scholar 

  11. Scorer CG, Farrington HG (1971) Congenital deformities of the testis and epididymis. Butterworths, London

    Google Scholar 

  12. Hecker WCh, Hienz HA, Mengel W (1972) Frühbehandlung des Maldenscensus testis. Dtsch Med Wochenschr 97:1325–1329

    Article  PubMed  CAS  Google Scholar 

  13. Brandesky G, Regele H (1973) Histologische Untersuchungen beim Leistenhoden. Monatsschr Kinderheilkd 121:611–613

    PubMed  CAS  Google Scholar 

  14. Jendricke K, Rager K, Schäfer E, Reisert I (1973) Vorläufige Ergebnisse klinischer, biochemischer und anatomischer Untersuchungen bei Maldescensus testis. Kinderheilkd 121:634–635

    CAS  Google Scholar 

  15. Dougall AJ, McLean N, Wilkinson AW (1974) Histology of the maldescended testis at operation. Lancet 1:771–774

    Article  PubMed  CAS  Google Scholar 

  16. Knecht H (1976) Tubulusstruktur und Keimzellverteilung in frühkindlichen kryptorchen und normalen Hoden. Beitr Pathol 159:249–270

    Article  PubMed  CAS  Google Scholar 

  17. Meyer JM, Goldschmidt PA, Sauvage P, Buck P (1977) Etude histologique et histométrique du testicule ectopique en fonction de l’âge. Incidences thérapeutiques. Ann Chirur Infant [Paris] 18:371–378

    Google Scholar 

  18. Reisert I, Steinhardt B, Flach A, Tonutti E (1977) Spermatogonienzahl in descendierten und nicht descendierten präpuberalen Hoden. Monatsschr Kinderheilkd 125:82–87

    PubMed  CAS  Google Scholar 

  19. Hedinger Chr (1979) Histological data in cryptorchidism. In: Job JU (ed) Cryptorchidism. Pediatric Adolescent Endocrinology, Karger, Basel

    Google Scholar 

  20. Houissa S, Pape J de, Diebold N, Feingold J, Nezelof C (1979) Cryptorchidism. Histological study of 220 biopsies with clinico-anatomical correlations. In: Job JU (ed) Cryptorchidism, Pediatric Adolescent Endocrinology, Karger, Basel

    Google Scholar 

  21. Lüdin A (1977) Histometrische Untersuchungen an den Spermatogonien bei kryptorchen Knaben. Med. Dissertation Universität Basel

    Google Scholar 

  22. Balze de la FA, Mancini RE, Arrillaga F, Andrada JA, Vilar O, Gurtmann AI, Davidson OW (1960) Histologic study upon the undescended human testis during puberty. J Clin Endocrinol 20:286–297

    Article  Google Scholar 

  23. Mancini ER, Rosenberg E, Cullen M, Lavieri CJ, Vilar O, Bergada C, Andrada AJ (1965) Cryptorchid and scrotal human testis. I. Cytological, cytochemical and quantitative studies. J Clin Endocrinol 25:927–942

    Article  CAS  Google Scholar 

  24. Georgiev G, Markov D (1970) Histological changes in undescended testis. Sur Sci Med Verena 8:109–111

    Google Scholar 

  25. Leeson CR (1966) An electronmicroscopic study of cryptorchid and scrotal human testes, with special reference to pubertal maturation. Invest Urol 3:498–511

    PubMed  CAS  Google Scholar 

  26. Bustos-Obregón E (1980) Peritubular tissue. In: Hafez ESE (ed) Descended and cryptorchid testis. Martinus Nijhoff, The Hague Boston London

    Google Scholar 

  27. Usadel HK, Schwedes U, Kollmann F, Dethe G (1977) Histological results of testis under normal conditions and in the development of primary hypogonadism in maldescensus testis. In: Maldescensus testis. Bierich RJ, Roger K, Ranke BM (eds) Urban &Schwarzenberg, München Wien Baltimore

    Google Scholar 

  28. Hayashi H, Harrison RG (1969) The development of the interstitial tissue of the human testis. Fertil &Steril 22:351–355

    Google Scholar 

  29. Numanoglu I, Köktürk I, Mutaf O (1969) Light and electronmicroscopic examinations of undescended testicles. J Pediatr Surg 4:614–619

    Article  PubMed  CAS  Google Scholar 

  30. Bergada C, Mancini ER (1973) Effect of gonadotropins in the induction of spermatogenesis in human prepubertal testis. J Clin Endocrinol Metab 37:935–943

    Article  PubMed  CAS  Google Scholar 

  31. Weissbach L, Heinemann I, Goslar GH (1975) Histochemische Untersuchungen beim experimentellen unilateralen Kryptorchismus des Hundes nach HCG-Behandlung. Acta Histochem 52:62–70

    PubMed  CAS  Google Scholar 

  32. Baker GT, Scrimgeour BJ (1980) Development of the gonad in normal and aneneephalic human fetuses. J Reprod Fertil 60:193–199

    Article  PubMed  CAS  Google Scholar 

  33. Ankerhold J, Gressmann C (1969) Hodendescensusstörungen beim frühkindlichen Hirnschaden. Z Kinderheilkd 107:15–25

    Article  PubMed  CAS  Google Scholar 

  34. Städtler F (1973) Die normale und gestörte präpubertale Hodenentwicklung des Menschen. Gustav Fischer, Stuttgart

    Google Scholar 

  35. Kaplan WG (1976) Iatrogenic cryptorchidism from hernia repair. Surg Gynecol Obstet 142:671–672

    PubMed  CAS  Google Scholar 

  36. Holstein FA, Körner F (1974) Light and electron microscopical analysis of cell types in human seminoma. Virchows Arch [Pathol Anat] 363:97–112

    Article  CAS  Google Scholar 

  37. Mostafi FK, Price BE (1973) Tumors of the male genital system. Armed Forces Institute of Pathology, Washington, D.C.

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Hadžiselimović, F. (1983). Histology and Ultrastructure of Normal and Cryptorchid Testes. In: Cryptorchidism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86020-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-86020-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-86022-5

  • Online ISBN: 978-3-642-86020-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics