Abstract
In this era of the coronary care unit and electrocardiographc monitoring of patients with acute myocardial infarction, a major problem is that of cardiogenic shock. Some 10 to 20 percent of hospitalized patients with acute myocardial infarction experience „pump failure“ or cardiogenic shock (2). Of these patients, 80 to 100 percent die as a direct result of the shock state (27). Various approaches to the management of this entity have been used by different investigators (11, 21, 29), and yet, a significant controversy exists as to the ideal therapeutic approach with a proper selection of various pharmacologic agents in cardiogenic shock.
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References
Abrams, E., Forrester, J. S., Chatterjee, K., Danzig, R., Swan, H. J. C. Variability in response to norepinephrine in acute myocardial infarction. Am. J. Cardiol., 32:919, 1973.
Binder, M. J., Ryan, J. A., Jr., Marcus, S., Mugler, F. Jr., Strange, D., and Agress, C. M. Evalua tion of therapy in shock following acute myocardial infarction. Am. J. Med., 18:622, 1955.
Braunwald, E. and Maroko, P. R. Protection of ischemic myocardium. In The Myocardium Failure and infarction. New York, H.P. Publications, 1974.
Chatterjee, K., Parmley, W., Ganz, W., Forrester, J., Walinsky, P., Crexells, C., and Swan, H. J. C. Hemodynamic and metabolic responses to vasodilator therapy in acute myocardial infarction. Circulation, 48:1183, 1973.
Cohn, J. N. and Luria, M. H. Studies in clinical shock and hypotension. II. Hemodynamic effects of norepinephrine and angiotensin. J. Clin. Invest., 44:1494, 1965.
Cohn, J. N.,Tristani, F. E., and Khatri, I. M. Cardiac and peripheral vascular effects of digitalis in clinical cardiogenic shock. Am. Heart J., 78:318, 1969.
Corday, E. and Swan, H. J. C. Myocardial Infarction. Baltimore, Williams and Wilkins, 1973.
Cox, J. L., McLaughlin, K. W., Flowers, N. C., and Horan, L. G. The ischemic zone surrounding acute myocardial infarction: its morphology as detected by dehydrogenase staining. Am. Heart J., 76:650, 1968.
Crexells, C., Chatterjee, K., Forrester, J. S., Dikshit, K., and Swan, H. J. C. Optimal level of filling pressure in the left side of the heart in acute myocardial infarction. N. Engl. J. Med., 289:1263, 1973.
Dietzman, R. H. and Lillehei, R. C. The treatment of cardiogenic shock. V. The use of cortico steroids in the treatment of cardiogenic shock. Am. Heart J., 75:274, 1968.
Dunkman, W. B., Leinbach, R. C., Buckley, M. J., Mundth, E. D., Kantrowitz, A. R., Austen, W. G., and Sanders, C. A. Clinical and hemodynamic results of intra aortic balloon pumping and surgery for cardiogenic shock. Circulation, 41:469, 1972.
Gorlin, R. Evaluation of myocardial metabolism in ischemic heart disease. Circulation Suppl. to Vol. XXXIX and XL, p. 155–163, 1969.
Gunnar, R. M. and Loeb, H. S. Use of drugs in cardiogenic shock due to acute myocardial infarc tion. Circulation, 45:1111, 1972.
Hanarceyan, C., Bennet, M. A., Pentecost, B. L., and Brewer, D. B. Quantitative study of infarcted myocardium in cardiogenic shock. Br. Heart J., 32:728, 1970.
Huddy, F. J. Pathophysiology and therapy of the shock of myocardial infarction. Ann. Intern. Med. 73:809, 1970.
Lefer, A. M., Cowgill, R., Marshall, F. F., Hall, L. M., and Brand, E. D. Characterization of a myocardial depressant factor present in hemorrhagic shock. Am. J. Physiol., 213:492, 1967.
Loeb, H. S., Rahimtoola, S. H., Rosen, K., Sunno, M. Z., Chyquimia, and Gunnar, R. Assessment of ventricular function after myocardial infarction by plasma volume expansion. Circulation, 47:720, 1973.
Loeb, H. S., Winslow, E., Rahimtoola, S. H., Rosen, K,, and Gunnar, R. Acute hemodynamic effects of dopamine in patients with shock. Circulation, 44:163, 1971.
Maroko, P. R., Kjekshus, J. K., Sobel, B. E., Watanabe, T., Covell, J. W., Ross, J. Jr., and Braunwald, E. Factors influencing infarct size following experimental coronary artery occlusion. Circulation, 43:67, 1971.
Mason, D. T. Digitalis pharmacology and therapeutics: Recent advances. Ann. Intern. Med., 80:520, 1974.
Misra, S. N. and Kezdi, P. Hemodynamic effects of adrenergic stimulating and blocking agents on cardiogenic shock and low output state after myocardial infarction. Am. J. Cardiol., 31:724,1973.
Morris, R. M., Brandt, P. W. T., Caughey, D. F., Lee, A. J., and Scott, P. J. A new coronary prognostic index. Lancet, 1:274, 1969.
Mueller, H. S., Ayres, S. M., Religa, A., and Evans, R. G. Acute myocardial infarction: effect on myocardial oxygenation and hemodynamics. Circulation, 49:1078, 1974.
Mueller, H. S., Ayres, S. M., Gianelli, S., Conklen, E. F., Mazzara, J. T., and Grace, W. J. Effect of isoproterenol, l-norepinephrine, and intra aortic counterpulsation on hemodynamics and myocardial infarction. Circulation, 45:335, 1972.
Mueller, H. S., Ayres, S. M., Gianelli, S. Jr., Conklin, E. F., Mazzara, J. T., and Grace, W. J. Effects of isoproterenol, L-norepinephrine and intra-aortic balloon counterpulsation on hemodynamics and myocardial metabolism in shock following acute myocardial infarction. Circulation, 45:335, 1972.
Mundth, E. D., Buckley, M. J., Leinbach, R. C., DeSanctis, R. W., Sanders, C. A., Kantrowitz, A., and Austen, W. G. Myocardial revascularization for the treatment of cardiogenic shock complicating acute myocardial infarction. Surgery, 70:78, 1971.
Nyquist, O. Shock complicating acute myocardial infarction. Acta Med. Scand. Suppl. 536, p. 54–63, 1972.
Page, D. L., Caulfied, J. B., Kastor, J. A., DeSanctis, R. W., and Sanders, C. A. Myocardial changes associated with cardiogenic shock. N. Engl. J. Med., 285:133, 1971.
Perlroth, M. G. and Harrison, D. C. Cardiogenic shock: A review. Clin. Pharmacol. Ther. 10:449, 1969.
Rackley, C. E. and Russel, R. O. Jr. Left ventricular function in acute myocardial infarction and its clinical significance. Circulation, 45:231, 1972.
Ratshin, R. A., Rackley, C. E., and Russel, R. O. Jr. Hemodynamic evaluation of left ventricular function in shock complicating myocardial infarction. Circulation, 45:127, 1972.
Scheidt, S., Wilner, G., Mueller, H., Summers, D., Lescn, M., Wolff, G., Krakauer, J., Ruberfire, M., Fleming, P., Noon, G., Aldham, N., Killip, T., and Kantrowitz, A. Intra-aortic balloon counterpulsation in cardiogenic shock. N. Engl. J. Med., 288:979, 1973.
Scheinman, M., Evans, G. T., Weiss, A., and Rapaport, E. Relationship between pulmonary artery end-diastolic pressure and left ventricular filling pressure in patients in shock. Circulation, 42:317, 1973.
Smullens, S. N., Wiener, L., Kasparian, H., Brest, A. N., Bacharach, B., Noble, P. H., and Templeton, J. Y. III. Evaluation and surgical management of acute evolving myocardial infarction. J. Thorac. Cardiovasc. Surg., 64:495, 1972.
Stock, E. Prognosis of myocardial infarction in a coronary care unit. Med. J. Austr. 2:377, 1969.
Swan, H. J. C., Forrester, J. S., Diamond, G., Chatterjee, K., and Parmley, W. Hemodynamic spectrum of myocardial infarction and cardiogenic shock. Circulation, 45:1097, 1972.
Talley, R. C., Goldberg, L. I., Johnson, C. E., and McNay, J. L. A hemodynamic comparison of dopamine and isoproterenol in patients with shock. Circulation. 39:361, 1969.
Vander Ark, C. R. and Reynolds, E. W. Clinical evaluation of glucagon by continuous infusion in the treatment of new cardiac output states. Am. Heart J., 79:481, 1970.
Walinsky, P., Chatterjee, K., Forrester, J., Parmely, W., and Swan, H. J. C. Enhanced left ventricular performance with phentolamine in acute myocardial infarction. Am. J. Cardiol., 33:37, 1974.
Wiener, L. Personal communication.
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Weisberger, C.L., Ruggiero, N., Chung, E.K. (1976). Treatment of Cardiogenic Shock. In: Chung, E.K. (eds) Controversy in Cardiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86000-3_5
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DOI: https://doi.org/10.1007/978-3-642-86000-3_5
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