Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites

  • H. R. Schäfer

Abstract

All pharmacokinetic studies dealing with primidone therapy are complicated because phenobarbitone and phenylethylmalondiamide (PEMA) are the main metabolites of the biotransformation of primidone.

Keywords

Carbamazepine Biotransformation Phenobarbital Barbiturate Phenobarbitone 

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References

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Copyright information

© Springer-Verlag Berlin-Heidelberg 1975

Authors and Affiliations

  • H. R. Schäfer
    • 1
  1. 1.Chemisch-pharmazeutisches LaboratoriumDesitin-Werk Carl Klinke G.m.b.H.Hamburg 63Federal Republic of Germany

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