Menopause is the cessation of menses. The climacteric (perimenopause) is the 10–20 year period around this point. The median age is 50 years, irrespective of race, socioeconomic status, parity, height or weight. In smokers it occurs 1–2 years earlier. It is due to a decline in the supply of ovarian follicles (oocytes) by atresia, a process which begins after the 20th week of intrauterine life.
KeywordsHormone Replacement Therapy Ovarian Follicle Endometrial Hyperplasia Vasomotor Symptom Clinical Obstetric
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