On the Prevention and Treatment of Choriocarcinoma

  • Constantino P. Manahan
  • Rainerio Abad
  • Anatalia M. Lopez
Part of the UICC Monograph Series book series (UICC, volume 3)

Abstract

In trying to account for the confusion and the many attempts at classifying mole, chorioadenoma destruens and choriocarcinoma, it seemed to us that the difficulty was in considering these entities as three separate and distinct conditions rather than accepting them as stages in the progression from a benign state, hydatidiform mole, to a highly malignant phase, choriocarcinoma. All these stages may be present in one patient at the same time. The histopathologic features of each of these conditions are universally accepted. While these categories differ in pathologic findings and in behavior, they may be better understood if they are pictured as one condition which we prefer to call trophoblastic disease [neoplasia — Ed].

Keywords

Toxicity Adenoma Methotrexate Noma Choriocarcinoma 

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References

  1. Acosta-Sison, H., Our changed attitude in the management of hydatidiform mole in 196 cases admitted to the Philippine General Hospital from April 10, 1959 to March 27, 1963. Phil J. Surg. 19, 227–231 (1964).Google Scholar
  2. Manahan, C. P., Benitez, I., and Estrella, F., Amethopterin in the treatment of trophoblastic tumors. Amer. J. Obstet. Gynec. 82, 641–645 (1961).PubMedGoogle Scholar
  3. Manahan, C. P., Manuel-Limson, G., and Abad, R., Experience with choriocarcinoma in the Philippines. Ann. N. Y. Acad. Sci. 114, 875–880 (1964).CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1967

Authors and Affiliations

  • Constantino P. Manahan
    • 1
  • Rainerio Abad
    • 1
  • Anatalia M. Lopez
    • 1
  1. 1.Department of Obstetrics and Gynecology, College of MedicineUniversity of the Philippines and the Philippine General HospitalManilaPhilippines

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