Calcium Entry Blockers in Migraine: The State of the Art

  • E. L. H. Spierings
Conference paper


The calcium entry blockers or calcium antagonists are a group of medications that share the potential of inhibiting the movement of calcium into cells and cell organelles. They do so through a number of different mechanisms, such as, for instance, the blockade of potential- or receptor-operated calcium channels or the blockade of calcium influx under conditions of overload. Chemically the calcium entry blockers represent medications of different groups with little or no relationship to each other and little or no predictability with regard to activity and/or mechanism [24].


Cerebral Blood Flow Cluster Head Cluster Headache Migraine Attack Spreading Depression 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • E. L. H. Spierings
    • 1
    • 2
  1. 1.The Headache Research Foundation and John R. Graham Headache CentreThe Faulkner HospitalUSA
  2. 2.Department of NeurologyTufts University School of MedicineBostonUSA

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