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Suppression of Brain and Adrenal Gland Arteriosclerosis by Calcium Antagonism in Hypertensive Rats (Skelton Hypertension)

  • P. E. Schwabedal
Conference paper

Abstract

Rats develop hypertension following Skelton’s treatment, i.e., (a) unilateral adrenalectomy and contralateral adrenal enucleation, (b) unilateral nephrectomy, and (c) administration of 1% NaCl with the drinking fluid (Skelton 1959). The pathogenesis of Skelton hypertension is still obscure. But in this hypertension model the adrenal operation (a) can be substituted by stress (Deane and McKibbin 1946) due to pantothenic acid deficiency (Schwabedal et al. 1985) and the nephrectomy (b) by means of a slight reduction in the kidney blood perfusion (Schwabedal 1987 a, 1988 a).

Keywords

Adrenal Gland Frontal Section Unilateral Nephrectomy Adrenal Operation Unilateral Adrenalectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • P. E. Schwabedal
    • 1
  1. 1.Institute of AnatomyUniversity of BonnBonn 1Germany

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