Abstract
According to present knowledge any physiological or pharmacological stimulus somewhere in the chain of events occurring between fixation of an agent to its binding sites or receptor and final response requires ionized calcium (Ca2+) as a mediator (ionic messenger). This concerns a variety of physiological events like smooth, skeletal, and heart muscle contraction, exocytosis, phagocytosis, axonal transport, cell shape changes, cilial movement, cell division, sperm motility, conductance changes for other ions and for calcium itself, and regulation of metabolic activities (e.g., lipase and protein kinase activation), to give only a few examples. Proper physiological activation is, however, bound to a graded cytosolic increase of Ca2+ of well-controlled duration.
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© 1989 Springer-Verlag Berlin Heidelberg
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Peters, T. (1989). Cellular Movements and Distribution of Calcium. In: Hartmann, A., Kuschinsky, W. (eds) Cerebral Ischemia and Calcium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85863-5_4
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DOI: https://doi.org/10.1007/978-3-642-85863-5_4
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