Roles of Calcium-Activated Enzymic Reactions in Ischemia-Induced Neuronal Injury
Temporal ischemia of the brain injures only the selectively vulnerable brain cells. All of these neurons are constituents of either the limbic system or the basal ganglia, and recipients of the glutamatergic fibers. Recent studies in our laboratories unveiled that postischemic injury of these neurons is caused not by the energy failure but by dysfunction of the intracellular signal transducing system.
KeywordsForebrain Ischemia Inositol Trisphosphate Calcium Blocker Temporal Ischemia Postischemic Injury
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