Regional Cerebral Blood Flow After Cryoinjury of the Rabbit Brain
Head injury or ischemia induces focal cerebral lesions with subsequent development of brain edema. The pathological water accumulation may affect CBF in surrounding areas (Frei et al. 1973). Impairments of the local oxygen supply may then result in further damage to the brain. A rabbit model was established in this laboratory to characterize the spatial and time-dependent changes of rCBF and of the brain surface oxygen partial pressure (tissue PO2) after focal cold injury to the brain.
KeywordsPermeability Depression Ischemia Platinum Neurol
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