Abstract
In a previous communication [2] we have described a new mathematical model for the analysis of cerebral clearance curves consisting of a bimodal Gaussian distribution of exponentials. The purpose of the present communication is to further evaluate this bimodal Gaussian model and to compare it with the two compartment model using cerebral clearance curves synthetized from regional cerebral blood flow data obtained in cats.
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Berman, M., E. Shahn, and M. F. Weiss: The routine fitting of kinetic data to models: A mathematical formalism for digital computers. Biophys. J. 2, 275 (1962).
Reivich, M.: Observations on experimental models of cerebral clearance curves. In: Research on the Cerebral Circulation. J. S. Meyer (Ed.). Springfield: Charles C. Thomas 1969. III.
Reivich, M., J. Jehle, L. Sokoloff, and S. S. Kety: Measurement of regional cerebral blood flow with C14-antipyrine in awake cats. J. appl. Physiol., 1969, in press.
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© 1969 Springer-Verlag Berlin · Heidelberg
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Reivich, M., Slater, R., Sano, N. (1969). Further Studies on Exponential Models of Cerebral Clearance Curves. In: Brock, M., Fieschi, C., Ingvar, D.H., Lassen, N.A., Schürmann, K. (eds) Cerebral Blood Flow. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85860-4_3
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DOI: https://doi.org/10.1007/978-3-642-85860-4_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-85862-8
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