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Dependence of 85Kr(β)-Clearance rCBF Determination on the Input Function

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Abstract

Two procedures have been proposed for the quantitative determination of rCBF by analysis of radioactive inert gas clearance curves, following intra-arterial injection:

  1. 1.

    the slope-method [1],

  2. 2.

    the height-over-area-method [4].

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References

  1. Ingvar, D. H., and N. A. Lassen: Regional Blood Flow of the Cerebral Cortex Determined by Krypton 85. Acta physiol. scand. 54, 325 (1962).

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  2. Hutten, H.: The influence of Diffusion of Inert Gases on the Determination of Blood Flow by the Clearance Method. III. International Symposium: Cerebral Blood Flow and Cerebro-Spinal Fluid. Lund-Copenhagen, Scand. J. Clin. Lab. Invest., Suppl. 102, p. II-C, 1968.

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  3. Lassen, N. A., K. Hoedt-Rasmussen, S. C. Sorensen, E. Skinhoj, S. Cronquist, B. Bodforss, and D. H. Ingvar: Regional Cerebral Blood Flow In Man Determined By Krypton 85. Neurology 13, 719 (1963).

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  4. Zierler, K. L.: Equations for Measuring Blood Flow by External Monitoring of Radioisotopes. Circulat. Res. 16, 309 (1965).

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© 1969 Springer-Verlag Berlin · Heidelberg

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Hutten, H., Schwarz, W., Schulz, V. (1969). Dependence of 85Kr(β)-Clearance rCBF Determination on the Input Function. In: Brock, M., Fieschi, C., Ingvar, D.H., Lassen, N.A., Schürmann, K. (eds) Cerebral Blood Flow. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85860-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-85860-4_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85862-8

  • Online ISBN: 978-3-642-85860-4

  • eBook Packages: Springer Book Archive

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