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Dependence of 85Kr(β)-Clearance rCBF Determination on the Input Function

  • H. Hutten
  • W. Schwarz
  • V. Schulz

Abstract

Two procedures have been proposed for the quantitative determination of rCBF by analysis of radioactive inert gas clearance curves, following intra-arterial injection:
  1. 1.

    the slope-method [1],

     
  2. 2.

    the height-over-area-method [4].

     

Keywords

Cerebral Blood Flow Input Function Injection Time Sinusoidal Wave Injection Duration 
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References

  1. 1.
    Ingvar, D. H., and N. A. Lassen: Regional Blood Flow of the Cerebral Cortex Determined by Krypton 85. Acta physiol. scand. 54, 325 (1962).CrossRefGoogle Scholar
  2. 2.
    Hutten, H.: The influence of Diffusion of Inert Gases on the Determination of Blood Flow by the Clearance Method. III. International Symposium: Cerebral Blood Flow and Cerebro-Spinal Fluid. Lund-Copenhagen, Scand. J. Clin. Lab. Invest., Suppl. 102, p. II-C, 1968.CrossRefGoogle Scholar
  3. 3.
    Lassen, N. A., K. Hoedt-Rasmussen, S. C. Sorensen, E. Skinhoj, S. Cronquist, B. Bodforss, and D. H. Ingvar: Regional Cerebral Blood Flow In Man Determined By Krypton 85. Neurology 13, 719 (1963).PubMedCrossRefGoogle Scholar
  4. 4.
    Zierler, K. L.: Equations for Measuring Blood Flow by External Monitoring of Radioisotopes. Circulat. Res. 16, 309 (1965).PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1969

Authors and Affiliations

  • H. Hutten
    • 1
  • W. Schwarz
    • 1
  • V. Schulz
    • 1
  1. 1.Physiological InstituteUniversity of MainzGermany

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