The Relationship between Swelling of Hard Tissue Collagen in Acid and Alkali and the Presence of Phosphate Cross-links
While the swelling characteristics of soft tissue collagens have been extensively studied (Bowes and Kenten, 1950 a, b) only recently has attention been directed to similar studies of hard collagenous tissue. This latter work has arisen from the observation that the solubility of dentine collagen is very much less than that of corium collagen and this has been attributed to differences in the type or extent of intermolecular stabilisation in these two materials (Veis and Schlueter, 1963). More recently (Veisand Schlueter, 1964; Schlueter and Vets, 1964) it has been proposed that specific phosphate diester bonds are involved in cross-linking dentine collagen and that these esters are attached to the polypeptide chains through serine.
KeywordsSodium Hydroxide Phosphorus Content Hydrochloric Acid Solution Bone Collagen Potassium Dihydrogen Phosphate
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