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State of the Art: Lucké Renal Adenocarcinoma

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Biology of Amphibian Tumors

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 1969))

Abstract

Amphibians are subject to the same range of neoplasms found in higher vertebrates; renal adenocarcinomas, lymphomas, lymphosarcomas, plasmacytomas and melanomas are among those which have been described. The Lucké tumor, a renal adenocarcinoma of the leopard frog, Rana pipiens, is undoubtedly the best understood of these cold-blooded tumors. This transmissable tumor has become the subject of increasingly intensified interest because of recent significant contributions to an understanding of its suspected viral etiology.

Aided by grant #E-494 from the American Cancer Society.

The Chapman H. Hyams III Laboratory of Tumor cell Biology.

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References

  1. Anderson, N. G.: The development of zonal centrifuges and ancillary systems for tissue fractionation and analysis. Monograph 21, Natl. Cancer Inst., Bethesda, 1966, 526 pp.

    Google Scholar 

  2. Came, P. E., G. Geering, L. J. Old and E. A. Boyse: A serological study of polyhedral cytoplasmic viruses isolated from Amphibia. Virology 36:392–400, 1968.

    Article  PubMed  CAS  Google Scholar 

  3. Came, P. E. and P. D. Lunger: Viruses isolated from frogs and their relationship to the the Lucke tumor. Arch. f. ges. Virusforschung 19:464–468, 1966.

    Article  CAS  Google Scholar 

  4. Clark, H. F., C. Gray, F. Fabian, R. Zeigel and D. T. Karzon: Comparative studies of amphibian cytoplasmic virus strains isolated from the leopard frog, bullfrog and newt. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 310–326.

    Google Scholar 

  5. DiBerardino, M. A., T. J. King and R. G. McKinnell: Chromosome studies of a frog renal adenocarcinoma line carried by serial intraocular transplantation. J. Natl. Cancer Inst. 31:769–789, 1963.

    PubMed  CAS  Google Scholar 

  6. Fawcett, D. W.: Electron microscope observations on intracellular virus-like particles associated with the cells of the Lucke renal adenocarcinoma. J. Biophys. Biochem. Cytol. 2:725–742, 1956.

    Article  PubMed  CAS  Google Scholar 

  7. Fink, M. A., G. S. King and M. Mizell: Preliminary note: identity of a herpesvirus antigen from Burkitt lymphoma of man and the Lucke adenocarcinoma of frogs. J. Natl. Cancer Inst. 41:1477–1478, 1968.

    PubMed  CAS  Google Scholar 

  8. Fink, M. A., G. S. King and M. Mizell: Reactivity of serum from frogs and other species with a herpesvirus antigen extracted from a Burkitt lymphoma cultured cell line. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 358–364.

    Google Scholar 

  9. Freed, J. J. and S. J. Rosenfeld: Frog renal adenocarcinoma: cytological studies in situ and in vitro. Ann. N.Y. Acad. Sci. 126:99–114, 1965.

    Article  PubMed  CAS  Google Scholar 

  10. Granoff, A., P. E. Came and K. A. Rafferty, Jr.: The isolation and properties of viruses from Kana pipicns: their possible relationship to the renal adenocarcinoma of the leopard frog. Ann. N.Y. Acad. Sci. 126:237–255, 1965.

    Article  PubMed  CAS  Google Scholar 

  11. King, T. J. and M. A. DiBerardino: Transplantation of nuclei from the frog renal adenocarcinoma I. Development of tumor nuclear-transplant embryos. Ann. N.Y. Acad. Sci. 126:11 5–126, 1965.

    Google Scholar 

  12. Kirkwood, J. M., G. Geering, L. J. Old, M. Mizell and J. Wallace: A preliminary report on the serology of Lucke and Burkitt herpestype viruses: a shared antigen. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 365–367.

    Google Scholar 

  13. Lucke, B.: A neoplastic disease of the kidney of the frog, Kana pipicns. Am. J. Cancer 20:352–379, 1934.

    Google Scholar 

  14. Lucke, B.: Carcinoma in the leopard frog: its probable causation by a virus. J. Exptl. Med. 68:457–468, 1938.

    Article  CAS  Google Scholar 

  15. Lucke, B.: Kidney carcinoma in the leopard frog: a virus tumor. Ann. N.Y. Acad. Sci. 54:1093–1109, 1952.

    Article  PubMed  CAS  Google Scholar 

  16. Lucke, B. and H. G. Schlumberger: The manner of growth of frog carcinoma, studied by direct microscopic examination of living intraocular transplants. J. Exper. Med. 70: 257–268, 1939.

    Article  CAS  Google Scholar 

  17. Lucke, B. and H. G. Schlumberger: Effects of roentgen rays on cancer. Direct microscopic observations on living intraocular transplants of frog carcinoma. J. Natl. Cancer Inst.11:511–543, 1950.

    PubMed  CAS  Google Scholar 

  18. Lunger, P. D.: The isolation and morphology of the Lucké frog kidney tumor virus. Virology 24:1 38–145, 1964.

    Google Scholar 

  19. Lunger, P. D.: Fine structure studies of cytoplasmic viruses associated with frog tumors. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 296–309.

    Google Scholar 

  20. Lunger, P. D., R. W. Darlington and A. Granoff: Cell-virus relationships in the Lucké renal adenocarcinoma: an ultrastructural study. Ann. N.Y. Acad. Sci. 126:289–314, 1965.

    Article  PubMed  CAS  Google Scholar 

  21. Mizell, M., C. W. Stackpole and S. Halperen: Herpes-type virus recovery from “virus-iree” frog kidney tumors. Proc. Soc. Exp. Biol, and Med. 127:808–814, 1968.

    CAS  Google Scholar 

  22. Mizell, M., C. W. Stackpole and J. J. Isaacs: Herpestype virus latency in the Lucké tumor. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 337–347.

    Google Scholar 

  23. Mizell, M., I. Toplin and J. J. Isaacs: Tumor induction in developing frog kidneys by a zonal centrifuge purified fraction of the frog herpes-type virus. Science, 165:1134–1137, 1969.

    Article  PubMed  CAS  Google Scholar 

  24. Mizell, M. and J. Zambernard: Viral particles of the frog renal adenocarcinoma: causative agent or passenger virus? II. A promising model system for the demonstration of a tclysogenic state in a metazoan tumor. Ann. N.Y. Acad. Sci. 126:146–169, 1965.

    Article  PubMed  CAS  Google Scholar 

  25. Morris, V. L., P. G. Spear and B. Roizman: Some biophysical properties of frog viruses and their DNA. Proc. Nat. Acad. Sci., USA. 56:1155–1157, 1966.

    Article  CAS  Google Scholar 

  26. Nu, S., C. Morgan and H. M. Rose: Electron microscopy of herpes simplex virus. II. Sequence of development. J. Virol. 2:517–536, 1968.

    Google Scholar 

  27. Patrizi, G., J. N. Middelkamp, J. C. Herweg and H. K. Thornton: Human cytomegalovirus: election microscopy of a primary viral isolate. J. Lab. Clin. Med. 65:825–838, 1965.

    PubMed  CAS  Google Scholar 

  28. Pluznik, D. H., L. Sachs and P. Resnitzky: The mechanism of leukemogenesis by the Rauscher leukemia virus. In Conference on Murine Leukemia (M. A. Rich and J. B. Moloney, eds.), Monograph 22, Natl. Cancer Inst., Bethesda, 1966, pp. 3–14.

    Google Scholar 

  29. Rafferty, K. A., Jr.: Kidney tumors of the leopard frog: a review. Cancer Res. 24:169–185, 1964.

    PubMed  Google Scholar 

  30. Rafferty, K. A., Jr.: The cultivation of inclusion-associated viruses from Lucké tumor frogs. Ann. N.Y. Acad. Sci. 126:3–21, 1965.

    Article  PubMed  Google Scholar 

  31. Schlumberger, H. and B. Lucke: Serial intraocular transplantation of frog carcinoma for fourteen generations. Cancer Res. 9:52–60, 1949.

    PubMed  CAS  Google Scholar 

  32. Shiratori, O., T. Osato and Y. Ito: “Induction” of viral antigen in established cell line (SP-8) derived from Shope virus-induced cutaneous papilloma of rabbits. Proc. Soc. Exp. Biol, and Med. 130:115–121, 1969.

    CAS  Google Scholar 

  33. Shumway, W.: Stages in the normal development of Rana pipiens. Anat. Ree. 78:139–148, 1940.

    Article  Google Scholar 

  34. Taylor, A. C. and J. J. Kollros: Stages in the normal development of Rana pipiens larvae. Anat. Ree. 94:7–23, 1946.

    Article  CAS  Google Scholar 

  35. Toplin, I., P. Brandt and P. Sottong: Density gradient centrifugation studies on the herpes-type virus of the Lucké tumor.In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 348–357.

    Google Scholar 

  36. Tournier, P., F. Cathala and W. Bernhard: Ultrastructure et développement intracellulaire du virus de la varicelle observé au microscope électronique. Press Med. 52:1230–1235, 1957.

    Google Scholar 

  37. Tweedell, K. S.: Renal tumor transmission in frog embryos by subcellular fractions. Am. Zool. 5:171–172, 1965.

    Google Scholar 

  38. Tweedell, K. S.: Induced oncogenesis in developing frog kidney cells. Cancer Res. 27: 2042–2052, 1967.

    Google Scholar 

  39. Tweedell, K. S.: Simulated transmission of renal tumors in oocytes and embryos of Kana pipicns. In Biology of Amphibian Tumors (M. Mizell, ed.), Springer-Verlag New York Inc., 1969, pp. 229–239.

    Google Scholar 

  40. Tweedell, K. S. and A. Granoff: Viruses and renal carcinoma of Kana pipiens. V. Effect of frog virus 3 on developing frog embryos and larvae. J. Natl. Cancer Inst. 40:407–410, 1968.

    PubMed  CAS  Google Scholar 

  41. Zambernard, J. and M. Mizell: The fine structure of the frog renal adenocarcinoma before and during intraocular transplantation. Am. Zool. 3: 511, 1963.

    Google Scholar 

  42. Zambernard, J. and M. Mizell: Viral particles of the frog renal adenocarcinoma: causative agent or passenger virus? I. Fine structure of primary tumors and subsequent intraocular transplants. Ann. N.Y. Acad. Sci. 226:127–145, 1965.

    Google Scholar 

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Mizell, M. (1969). State of the Art: Lucké Renal Adenocarcinoma. In: Mizell, M. (eds) Biology of Amphibian Tumors. Recent Results in Cancer Research, vol 1969. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85791-1_1

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  • DOI: https://doi.org/10.1007/978-3-642-85791-1_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85793-5

  • Online ISBN: 978-3-642-85791-1

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