Photoselection and Linear Dichroism of Retinal Isomers and Visual Pigments

  • Joram Heller
  • Joseph Horwitz


It has been known for about ten years that when frozen solutions (glasses) of visual pigments at 77°K are illuminated with visible light, there are changes in the absorption spectrum of the pigments (1, 2, 3). These changes in the absorption spectrum, which in general are fairly small (less than 20 nm shifts in the absorption maxima), are dependent on the wavelength of the illuminating light and show the typical behavior of the photochromic systems.


Sodium Dodecyl Sulfate Schiff Base Visual Pigment Linear Dichroism Circular Dichroism Band 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    YOSHIZAWA, T., G. WALD: Pre-lumirhodopsin and the bleaching of visual pigments. Nature (Lond.) 197, 1279–1286 (1963).CrossRefGoogle Scholar
  2. 2.
    YOSHIZAWA, T., G. WALD: Transformations of squid rhodopsin at low temperatures. Nature (Lond.) 201, 340–345 (1964).CrossRefGoogle Scholar
  3. 3.
    YOSHIZAWA, T., G. WALD: Photochemistry of iodopsin. Nature (Lond.) 214, 566–571 (1967).CrossRefGoogle Scholar
  4. 4.
    BECKER, R.S., K. INUZUKA, J. KING, D.E. BALKE: Comprehensive investigation of the spectroscopy and photochemistry of retinals. II. Theoretical and experimental consideration of emission and photochemistry. J. Am. Chem. Soc. 93, 43–50 (1971).PubMedCrossRefGoogle Scholar
  5. 5.
    KROPF, A., R. HUBBARD: The mechanism of bleaching rhodopsin. Ann. NY Acad. Sci. 74, 266–280 (1958).CrossRefGoogle Scholar
  6. 6.
    IRVING, C.S., G.W. BYERS, P.A. LEERMAKERS: Spectroscopic model for the visual pigments. Influence of microenvironmental polarizability. Biochemistry 9, 858–864 (1970).PubMedCrossRefGoogle Scholar
  7. 7.
    CRESCITELLI, F., W.F.H.M. MOMMAERTS, T.I. SHAW: Circular dichroism of visual pigments in the visible and ultraviolet spectral regions. Proc. Nat. Acad. Sci. USA 56, 1729–1734 (1966).PubMedCrossRefGoogle Scholar
  8. 8.
    WAGGONER, A.S., L. STRYER: Induced optical activity of the metarhodopsins. Biochemistry 10, 3250–3254 (1971).PubMedCrossRefGoogle Scholar
  9. 9.
    HONIG, B., M. KARPLUS: Implications of torsional potential of retinal isomers for visual excitation. Nature (Lond.) 229, 558–560 (1971).CrossRefGoogle Scholar
  10. 10.
    SUNDARALINGAM, M., C. BEDDELL: Structures of the visual chromophores and related pigments: A conformational basis of visual excitation. Proc. Nat. Acad. Sci. USA 69, 1569–1573 (1972).PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1973

Authors and Affiliations

  • Joram Heller
    • 1
  • Joseph Horwitz
    • 1
  1. 1.Jules Stein Eye InstituteUCLA School of MedicineLos AngelesUSA

Personalised recommendations