Recovery of Axonal Transport of Acetylcholinesterase in Regenerating Sciatic Nerve Precedes Muscle Reinnervation

  • Luigi Di Giamberardino
  • Jean-Yves Couraud
  • Raymonde Hässig
  • Alfredo Gorio
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


Recent reports have shown that the effect of nerve trauma on the axonal transport of acetylcholinesterase (AChE) may differ depending on the type of injury. While the axonal transport of AChE was seen to decrease drastically during the 2-3 days following nerve injury, whatever the injury [3, 5, 7], the recovery which followed this initial drop was seen to take place only after nerve crush [5,7] or nerve freezing [5] but not after nerve section and very little after nerve ligature [5].


Sciatic Nerve AChE Activity Axonal Transport Nerve Segment Sciatic Nerve Crush 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Luigi Di Giamberardino
    • 1
    • 3
  • Jean-Yves Couraud
    • 1
  • Raymonde Hässig
    • 1
  • Alfredo Gorio
    • 2
  1. 1.Déparment de BiologieCommissariat à l’Energie AtomiqueGif-sur-YvetteFrance
  2. 2.FIDIA Research LaboratoriesAbano TermeItaly
  3. 3.INSERUM U. 153,ParisFrance

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