Juxtaglomerular cells as the source of renin
As Professor BOHLE has so beautifully illustrated in his presentation, juxtaglomerular (JG) cells are in close anatomical association with macula densa and Polkissen or lacis cells. Both light and electron microscopy have provided evidence for the secretory nature of JG cells and it is assumed that macula densa is intimately involved functionally, but as yet the mechanism is unclear.
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- For a more detailed discussion including references and illustrations please see the following recent articles: Hartroft, P. M.: Juxtaglomerular Cells. Circ. Res. 12, 525, 1963.Google Scholar
- Bing, J.: Morphological Aspects of the Renin-Angiotensin System. Danish Med. Bull. 2, 24, 1964.Google Scholar
- Hartroft, P.M., Sutherland, L. E., and Hartroft, W. S.: JG Cells as a Source of Renin: Further studies with the fluorescent antibody technique and the effect of passive transfer of antirenin, Canad. Med. Assn. J. 90, 163, 1964.Google Scholar
- Hartroft, P. M.: The Juxtaglomerular Complex. Ann. Rev. Med. (in press).Google Scholar