Skip to main content

Die Niere als Bildungsstätte von Erythropoietin

  • Conference paper
Aktuelle Probleme der Nephrologie

Zusammenfassung

Hätte das Symposion über “endokrine Funktionen der Niere” 1955 und nicht erst 1965 stattgefunden, so wäre es früher zu Ende gegangen. Das erste Thema des heutigen Vormittages wäre mit Sicherheit ausgefallen. Von einer Substanz namens “Erythropoietin” wusste man damals wenig, von ihrer Beziehung zur Niere nichts. Inzwischen füllen Arbeiten über “Niere und Erythropoiese” die Fachzeitschriften der Physiologen, Kliniker und Pathologen, und die Erwähnung endokriner Einflüsse der Niere auf die Blutbildung hat längst nichts Sensationelles mehr an sich.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Andreadis, P., Bromig, G. u. Scharz, J.: Experimentelle Untersuchungen über die Bildung eines erythropoetischen Paktors in der Niere. Z. exp. Med. 138, 62–72 (1954).

    Article  Google Scholar 

  • Ardaillou, R., Najean, Y., Altman, J. u. Richet, G.: Étude de l’érythropoiese chez les rats néphrectomiesés et porteurs d’une autogreffe de rein. Rev. franc. clin. biol. 5, 189–190 (1960).

    CAS  Google Scholar 

  • Barath, E.: über den Hochdruck bei Nebennierenkrankheiten. (Braune und weiße Hypertonie. Pseudo-Cushing-Syndrom). Wiener klin. Wschr. j., 6, 295–298 (1943).

    Google Scholar 

  • Bialestock, D.: Anaemia of renal origin, studied by microdissection of the kidney. Australasian Ann. Med. 9, 44 (1960), zit. nach Leikin, 1964.

    CAS  Google Scholar 

  • Boivin, P., Lagrue, G. u. Fauvert, R.: L’activité érythropoiétique du plasma humain au cours de quelques affections hématologiques et autres. Nouv. Rev. franc. Hématol. 3, 35–50 (1963).

    CAS  Google Scholar 

  • Bradley, J.E., Young, J.D., jr., und Lentz, G.: Polycythemia secondary to pheochromocytoma. J. Urol. (Baltimore) 86, 1–6 (1961).

    Google Scholar 

  • Burk, D., Schade, A.L., Hesselbach, M.L. u. Fischer, C: Fed. Proc. 5, 126 (1946), zit. nach Levy, LEVISON und SCHADE (1950).

    PubMed  CAS  Google Scholar 

  • Burke, W.T. u. Morse, B.S.: Studies on the production and metabolism of erythropoietin in rat liver and kidney. In: Erythropoiesis. Edit. by L.O. Jacobson and Doyle, M. New York and London: Grune & Stratton (1962).

    Google Scholar 

  • Carnot, M.P. u. Deflandre, C1.: Sur l’activité hémopoiétique des différents organes au cours de la régénération du sang. C.R. Acad. Sci. (Paris) 143, 432–435 (1906).

    Google Scholar 

  • Carnot, M.P.: Sur le mécanisme de l’hyperglobulie provoquée par le sérum d’animaux en rénovation sanguine. C.R. Soc. biol. 61, 344–346 (1906).

    Google Scholar 

  • Cooper, G.W. u. Nocenti, M.R.: Unilateral renal ischaemia and erythropoietin. Proc. Soc. exp. Biol. (N.Y.) 108, 546–549 (1961).

    Google Scholar 

  • Cotes, M.: Persönliche Mitteilung an P. Hansen Demopoulos, H.B., Highman, B., Altland, P.D., Gerving, M.A. u. Kaley, G.: Effects of high altitude on granular juxtaglomerular cells and their possible role in erythropoietin production. Amer. J. Path. 46, 497–509 (1965).

    Google Scholar 

  • Durand, D. u. Sciaini, G.: Ricerche sperimentali sui rapporti tra rene et eritropoiesi. Pathologica 52, 499–506 (1960a).

    PubMed  CAS  Google Scholar 

  • Erslev, A.J.: Erythropoietic function in uremic rabbits. Arch. Int. Med. 101, 407–417 (1958).

    Article  CAS  Google Scholar 

  • Erslev, A.J.: In: Discussion of identity of erythropoietin and its site of production. In: The kinetics of cellular proliferation. New York and London: Grune & Stratton (1959), S. 361–363.

    Google Scholar 

  • Fisher, J.W. and Crook, J.J.: Influence of several hormones on erythropoiesis and oxygen consumption in the hypophysectomized rat. Blood 19, 557–565 (1962).

    PubMed  CAS  Google Scholar 

  • Fisher, J.W., Sanzari, N.P., Birdwell, B.J. u. Crook, J.J.: The role of the kidney in erythropoietin production. In: Jacobson and Doyle, Erythropoiesis. New York and London: Grune & Stratton (1962).

    Google Scholar 

  • Friend, D.G., Hoskins, R.G. u. Kirkin, M.W.: Relative erythrocythemia (polycythemia) and polycystic kidney diseases, with uremia: report of a case with comments on frequency of occurrence. New Engl. J. Med. 264, 17–19 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Gallagher, N., McCarthy, J.M., Hart, K.T. u. Lange, R.D.: Evaluation of plasma erythropoietic-stimulating factors in anemic uremic patients. Blood 14, 662–667 (1959).

    PubMed  CAS  Google Scholar 

  • Gallagher, N., McCarthy, J.M. u. Lange, R.D.: Observations on erythropoietic-stimulating factor (ESF) in the plasma of uremic and nonuremic anemic patients. Ann. Int. Med. 52, 1201–1212 (1960).

    PubMed  CAS  Google Scholar 

  • Göltner, E. u. Friederici, L.: Die erythropoetische Aktivität des Blutserums nach Blutverlusten bei Karzinomen ohne und mit urämie. Med. Welt (Stuttg.) 1962, 586-589.

    Google Scholar 

  • Goldfarb, B. u. Tobian, L.: Effect of high oxygen concentrations on erythropoietin and the renal juxtaglomerular cell. Proc. Soc. Exper. Biol. Med. 113, 35–36 (1963).

    CAS  Google Scholar 

  • Goldwasser, E. u. Dukes, P.P.: Unveröff., zit. nach Jacobson, Gurney u. Goldwasser: Adv. int. med. 10, 297–327 (1960).

    Google Scholar 

  • Gurney, C.W.: Erythropoietin, erythropoiesis and the kidney. J.A.M.A. 173, 1828 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Gurney, C.W., Goldwasser, E. u. Pan, C.: Studies on erythropoiesis. VI. Erythropoietin in human plasma. J. Lab. clin. Med. 50, 534–542 (1957).

    PubMed  CAS  Google Scholar 

  • Hansen, P.: Polycythemia produced by constriction of the renal artery in a rabbit. Acta path. microbiol. scand. 60, 465–472 (1964).

    PubMed  CAS  Google Scholar 

  • Hardwick, D.P., Strauss, J. u. Misrahy, G.A.: Kidney oxygen availability. Amer. J. Physiol. 205, 322–324 (1963).

    PubMed  CAS  Google Scholar 

  • Hartroft, Ph.M. u. Hartroft, W.S.: Studies on renal juxtaglomerular cells. I. Variations produced by sodium chloride and desoxycorticosterone acetate. J. Exper. Med. 97, 415 (1953).

    Article  CAS  Google Scholar 

  • Hashimoto, M. u. N. Nakamura: Study on bone marrow of autopsy cases in renal diseases, especially in chronic glomerulonephritis. J. Kyushu Hematol. Soc. 11, 158–192 (1961).

    Google Scholar 

  • Hearon, J., Schade, A.L., Levy, H. u. Burk, D.: Cobalt inhibition of tumor respiration and protection by histidine. Cancer Res. 7, 713 (1947).

    CAS  Google Scholar 

  • Hirashima, K.: Study on erythropoietic factor in plasma. Effects of human plasmas on the in vitro biosynthesis of heme by avian erythrocytes. Acta haemat. (Basel) 26, 209–223 (1961).

    Article  CAS  Google Scholar 

  • Hirashima, K. u. Takaku, F.: Experimental studies on erythropoietin. II. The relationship between juxtaglomerular cells and erythropoietin. Blood 20, 1–8 (1962).

    PubMed  CAS  Google Scholar 

  • Jacobson, L.O., Goldwasser, E., Fried, W. und Plzak, L.: Role of the kidney in erythropoiesis. Nature 179, 633–634 (1957).

    Article  PubMed  CAS  Google Scholar 

  • Jacobson, L.O., Goldwasser, E., Pried, W. u. Plzak, L.: Studies on erythropoiesis. VII. The role of the kidney in the production of erythropoietin. Trans. Ass. Am. Physic. 70, 305–317 (1957).

    CAS  Google Scholar 

  • Kaley, G. u. Demopoulos, H.B.: Effect of erythropoietic stimuli on renin content and juxtaglomerular cells. Fed. Proc. 22, 664 (1963).

    Google Scholar 

  • Keller, H.M.: La signification des hématopoiéties dans le développement des anémies observées au cours de néphropathies. I. Congr. Internat. Néphrol., Evian, 1960.

    Google Scholar 

  • Keller, H.M.: Diskussion zu C. Gasser: In: Hämolyse und hämolytische Erkrankungen. VII. Freiburger Symposium, Berlin-Göttingen-Heidelberg: Springer 1961.

    Google Scholar 

  • Keller, H.M. u. Khalifa, K.: Untersuchungen über Erythropoetin bei nephrektomierten Ratten, Acta haemat. (Basel) 29, 336–339 (1963).

    Article  CAS  Google Scholar 

  • Korst, E., Frenkel, E.P., Cousineau, L. u. Muirhead, E.E.: Erythropoietin studies in human renal abnormalities. Correlative renal explant attempts in the rat and dog. In: Erythropoiesis. Edit. By L.P. Jacobson and M. Doyle. New York and London, Grune & Stratton, 1962, p. 374–385.

    Google Scholar 

  • Krumdieck, N.: Erythropoietic substance in the serum of anemic animals. Proc. Soc. Exper. Biol. Med. 54, 14–17 (1943).

    CAS  Google Scholar 

  • Kuratowska, Z., Lewartowski, B. u. Lipinski, B.: Chemical and biological properties of an erythropoietin generating substance obtained from perfusates of isolated anoxic kidneys. J. Lab. Clin. Med. 64, 226–237 (1964).

    PubMed  CAS  Google Scholar 

  • Kuratowska, Z., Lewartowski, B. u. Michalak, E.: Studies on the site of erythropoietin productin. Proc. VIII. Europ. Congr. Hematol. Wien, 1961.

    Google Scholar 

  • Kuratowska, Z., Lewartowski, B. u. Michalak, E.: Studies on the production of erythropoietin by isolated perfused organs. Blood 18, 527–573 (1961 b).

    Google Scholar 

  • Leikin, S.L.: Hematologic aspects of renal disease. Ped. Clin. North Amer. 11, 667–684 (1964).

    CAS  Google Scholar 

  • Lessen, G.H. van, Stefanini, M., Smith, F.E.: Erythropoiesis after unilateral partial ligation of renal vein in dogs. Clin. Res. 6, 193 (1958).

    Google Scholar 

  • Mantz, J.M., Cholevas, M. u. Warter, J.: Études sur l’hémopoiétine chez le rat blanc. II. Arguments en faveur de son origine rénale. C.R. Soc. Biol. 154, 1068 (1960).

    CAS  Google Scholar 

  • Mc. Fadzean, A.J.S., Dodd, D. u. Tsang, K.C.: Polycethemia in primary carcinoma of the liver. Blood 13, 427–435 (1958).

    PubMed  CAS  Google Scholar 

  • Medvei, C.V.: über ein bemerkenswertes Zusammentreffen von Arthritis urica, Erythrämie Typ Vaquez und Hypernephroma malignum. Wiener Arch. inn. Med. 24, 417–426 (1934).

    Google Scholar 

  • Mirand, E.A. u. Prentice, T.C.: Presence of plasma erythropoietin in hypoxic rats with or without kidney (s) and/or spleen. Proc. Soc. Exper. Biol. Med. 96, 49–51 (1957).

    CAS  Google Scholar 

  • Mirand, E.A. u. Prentice, T.C.: The ability of hypophysectomized or hypophysectomized and nephrectomized rats to produce erythropoietin. Anat. Record 181, 581 (1958).

    Google Scholar 

  • Mirand, E.A., Prentice, T.C. u. Slaunwhite, W.R.: Current studies on the role of erythropoietin in erythropoiesis. Ann. N.Y. Acad. Sci. 77, 677–720 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Mitus, W.J. u. Toyama, K.: Role of juxtaglomerular apparatus in production of erythrocystosis in experimental hydronephrosis. X. Internat. Congr. Hematol. Stockholm, 1964.

    Google Scholar 

  • Muirhead, E.E. u. Kosinski, M.: Renomedullary origin of erythropoietin. X. Internat. Congr. Hematol. Stockholm, 1964.

    Google Scholar 

  • Naets, J.P.: Erythropoiesis in nephrectomized dog. Experentia 14/2, 74 (1958 a).

    Google Scholar 

  • Naets, J.P.: Erythropoiesis in nephrectomized dogs. Nature 181, 1134–1135 (1958).

    Article  PubMed  CAS  Google Scholar 

  • Naets, J.P.: The kidney and erythropoiesis. Nature 182, 1516–1517 (1958).

    Article  PubMed  CAS  Google Scholar 

  • Naets, J.P.: The role of the kidney in erythropoiesis. J. Clin. Invest. 39, 102–110 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Naets, J.P., Brauman, H. u. Kraytman, M.: Étude de l’érythropoiese au cours de l’insuffisance rénale aigue et chronique. Acta haemat. 24, 169–185 (1960).

    Article  CAS  Google Scholar 

  • Naets, J.P. u. Heuse, A.F.: Measurement of erythropoietic stimulating factor in anemic patients with or without renal disease. J. Lab. clin. Med. 60, 365–374 (1962 a).

    PubMed  CAS  Google Scholar 

  • Nakao, K.: Studies on erythropoietin. Acta haemat. japon. 25, 253–279 (1962).

    CAS  Google Scholar 

  • Nathan, D.G., Schupak, E., Stohlman, F. jr., Merrill, J.P.: Erythropoiesis in anephric man. J. Clin. Invest. 43, 2158–2165 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Noyes, W.D., Dom, B.M. u. Willis, L.C.: Regulation of erythropoiesis. I. Erythropoietin assay as a clinical tool. Blood 20, 9–18 (1962).

    PubMed  CAS  Google Scholar 

  • Osnes, S.: Influence of the pituitary on the erythropoietic principle produced in the kidney. Brit. Med. J. 1960 I, 1153–1157.

    Article  CAS  Google Scholar 

  • Pappenheimer, J.R. u. Kinter, W.B.: Hematocrit ratio of blood within mammalian kidney and its significance for renal hemodynamics. Amer. J. Physiol. 185, 377–390 (1956).

    PubMed  CAS  Google Scholar 

  • Penington, D.G.: The role of the erythropoietic hormone in anaemia. Lancet 1961 I, 301–306.

    Article  Google Scholar 

  • Reissmann, K.R. u. Nomura, T.: Erythropoietin formation in isolated kidneys and liver. In: Erythropoiesis. Edit. by L.O. Jacobson and M. Doyle. New York and London: Grune & Stratton, 1962, p. 71–77.

    Google Scholar 

  • Reissmann, K., Nomura, T., Gunn, R.W. u. Brosius, F.: Erythropoietic response to anemia or erythropoietin injection in uremic rats with or without functioning renal tissue. Blood 16, 1411–1423 (1960).

    PubMed  CAS  Google Scholar 

  • Remmele, W.: Die humorale Steuerung der Erythropoiese. Habil.-Schrift Heidelberg 1961, Berlin-Göttingen-Heidelberg: Springer 1963.

    Book  Google Scholar 

  • Remmele, W.: Hämopoietin. Verhandl. Dtsch. Ges. Path., Saarbrücken, 1965.

    Google Scholar 

  • Remmele, W., Mueller, K. u. Weber, J.: In Vorbereitung (1965).

    Google Scholar 

  • Richet, G., Alagille, D. u. Fournier, E.: L’érythroblastopénie aigue de l’anurie. Presse méd. 62, 50–53 (1954).

    PubMed  CAS  Google Scholar 

  • Richet, G., Ardaillou, R., Najean, Y. u. Méry, J.-Ph.: Polyglobulie survenue au cours de l’évolution d’une urémie chronique avec atrophie rénale. Etude isotopique de l’érythropoièse. Rev. franc. etud. clin.biol. 6, 909–912 (1961).

    PubMed  CAS  Google Scholar 

  • Rosse, W.F., Waldmann, T.A.: The role of the kidney in the erythropoietic response to hypoxia in parabiotic rats. Blood 19, 75–81 (1962).

    PubMed  CAS  Google Scholar 

  • Ruhenstroth-Bauer, G.: Versuche zum Nachweis eines spezifischen erythropoetischen Hormons. Arch. exp. path. Pharm. 211, 32–56 (1950).

    Article  CAS  Google Scholar 

  • Schmid, R. u. Gilbertsen, A.S.: Blood 10, 247 — (1955).

    PubMed  CAS  Google Scholar 

  • Schonfeld, A., Babbot, D. u. Gundersen, K.: Hypoglycemia and polycythemia associated with primary hepatoma. New Engl. J. Med. 265, 231–233 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Schretlen, E.D.A.M.: Erythropoietine. Centrale Drukkerij N.V. Nijmegen, 1963.

    Google Scholar 

  • Seljelid, R. u. Ericsson, J.L.E.: Electron microscopic observations on specializations of the cell surface in renal clear cell carcinoma. Lab. Invest. 14, 435–447 (1965).

    PubMed  CAS  Google Scholar 

  • Sokabe, H. u. Grollman, A.: Localization of blood pressure regulating and erythropoietic functions in rat kidney. Amer. J. Physiol. 203, 991–994 (1962).

    PubMed  CAS  Google Scholar 

  • Steinberg, B., Dietz, A.A. u. Atamer, M.A.: Mechanism of hematopoiesis. Hematopoietic regulators in serum albumin. Arch. Path. 67, 496–504 (1959).

    CAS  Google Scholar 

  • Steinberg, B., Dietz, A.A. u. Martin, R.A.: Mechanism of hematopoiesis. Hematopoietic effects of whole human and bovine serum. Lab. Invest. 7, 458–467 (1958).

    PubMed  CAS  Google Scholar 

  • Steinberg, B., Dietz, A.A. u. Martin, R.A.: Mechanism of hematopoiesis: hemacytopoietic factors in human plasma. Acta haemat. 21, 78–91, (1959).

    Article  PubMed  CAS  Google Scholar 

  • Stohlman, P. jr.: Regulation of erythropoiesis. Trans. N.Y. Acad. Sci. Ser. II, 24, 312–316 (1962a).

    Google Scholar 

  • Stohlman, F. jr.: Erythropoiesis. New Engl. J. Med. 267, 342–348 u. 392-399 (1962 b).

    Article  PubMed  Google Scholar 

  • Stohlman, F. jr., Rath, C.E. u. Rose, J.C.: Evidence for a humoral regulation of erythropoiesis. Studies on a patient with polycythemia secondary to regional hypoxia. Blood 9, 721–733 (1954).

    PubMed  Google Scholar 

  • Suki, W. u. Grollman, A.: Role of the kidney in erythropoiesis, Am. J. Physiol. 199, 629–632 (1960).

    CAS  Google Scholar 

  • Thorling, E. u. Jensen, K.: The effect of anemia and cobalt on lactic dehydrogenase isoenzymes and erythropoietin in kidney tissues of rabbits. X. Internat. Congr. Hematol. Stockholm, 1964.

    Google Scholar 

  • Warter, J., Mantz, M.M. und Hamann, B.: Recherches sur l’hémopoiétine (érythropoiétine). I. Pouvoir érythropoiétique du liquide de lavage du rein isolé et hypoxique de veau. C.R. Soc. Biol. 156, 897 (1962).

    CAS  Google Scholar 

  • Wesley, I.: A contribution to the problem of the mechanism of cobalt polycythemia. Arch. int. Physiol. 58, 412–414 (1951).

    Article  PubMed  CAS  Google Scholar 

  • Zollinger, H.: Diskussion zu Remmele, 1965.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1966 Springer-Verlag Berlin • Heidelberg

About this paper

Cite this paper

Remmele, W. (1966). Die Niere als Bildungsstätte von Erythropoietin. In: Krück, F. (eds) Aktuelle Probleme der Nephrologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85520-7_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-85520-7_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85521-4

  • Online ISBN: 978-3-642-85520-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics