Abstract
Large-scale epidemiological studies have shown that hypertension is associated with an increased rate of coronary artery disease, cerebrovascular disease, congestive heart failure, renal insufficiency, and peripheral artery disease, and that, therefore, cardiovascular morbidity, cardiovascular mortality, and overall mortality are greater in subjects with elevated blood pressure than in those in whom blood pressure is normal [1]. This has led researchers to conduct intervention trials that have proved the benefit of antihypertensive treatment, i. e., the fact that lowering elevated blood pressure leads to a reduction of the risk inherent in the hypertensive condition [2].
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References
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Mancia, G. (1991). Treatment of Hypertension and Prevention of Cardiovascular Morbidity and Mortality. In: Lichtlen, P.R., Reale, A. (eds) Adalat. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85498-9_8
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DOI: https://doi.org/10.1007/978-3-642-85498-9_8
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