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Peripheral physiological and pharmacological actions of indolealkylamines

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5-Hydroxytryptamine and Related Indolealkylamines

Abstract

5-Hydroxytryptamine base. Mouse, LD 50 by intravenous route: 160 mg/kg (Freyburger et al. 1952), 135 mg/kg (Higginbotham 1959); by intraperitoneal route: 280 mg/kg (Spencer and West 1961), 340 mg/kg (Fishel et al. 1962); by subcutaneous route: > 868 mg/kg (Freyburger et al. 1952). Rat, LD 50 by intravenous route: 30mg/kg; by subcutaneous route: approximately 117 mg/kg (Freyburger et al. 1952).

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Vittorio Erspamer

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© 1966 Springer-Verlag, Berlin · Heidelberg

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Erspamer, V. (1966). Peripheral physiological and pharmacological actions of indolealkylamines. In: Erspamer, V. (eds) 5-Hydroxytryptamine and Related Indolealkylamines. Handbook of Experimental Pharmacology/Handbuch der experimentellen Pharmakologie, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85467-5_7

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  • DOI: https://doi.org/10.1007/978-3-642-85467-5_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85469-9

  • Online ISBN: 978-3-642-85467-5

  • eBook Packages: Springer Book Archive

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