Zusammenfassung
Die portale Hypertonie gleich welcher Genese führt zur Ausbildung verschiedenster Gefäßverbindungen zwischen der portalen und der systemischen Zirkulation. Solange der Weg dieser Anastomosen nicht über Ösophagus und Magen führt, verursachen sie nur Enzephalopathie. Liegen die Kollateralgefäße aber in der Submukosa des Ösophagus oder des Magens, dann besteht ein hohes Risiko der Ruptur. Dieses Risiko der Ruptur ist wiederum wesentlich größer bei Ösophagusvarizen als bei Varizen im Magenfundus. Annähernd ein Drittel aller Patienten mit Leberzirrhose erleidet eine oder mehrere Ösophagusvarizenblutungen [1].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Benhamou JP (1983) Variceal bleeding. In: Postgraduate course: Hepatobiliary disease: Current concepts and controversies. The American Association for the Study of Liver Diseases, Chicago 1983
Lebrec D, De Fleury P, Rueff B, Nahum H, Benhamou JP (1980) Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis. Gastroenterology 79: 1139–1144
Viallet A, Marleau D, Huet M, Martin F, Farley A, Villeneuve JP, Lavoie P (1975) Hemodynamic evaluation of patients with intrahepatic portal hypertension: Relationship between bleeding varices and the portohepatic gradient. Gastroenterology 69: 1297–1300
Reynolds TB, Redeker AG, Geller HM (1957) Wedged hepatic venous pressure. A clinical evaluation. Am J Med 22: 341–350
Krook H (1957) Circulatory studies in liver cirrhosis. Acta Med Scand [Suppl] 318: 55–65
Brunner H, Grabner G, Paumgartner G, Schreiber V (1969) Klinische Aspekte der portalen Hypertension. Untersuchungen mittels Lebervenenkatheterismus an 286 Patienten. Wien Z Inn Med 50: 335–359
Simert G, Lunderquist A, Tylen U (1978) Correlation between percutaneous transhepatic portography and clinical findings in 56 patients with portal hypertension. Acta Chir Scand 144: 27–34
Smith–Laing G, Camilo ME, Dick R, Sherlock S (1980) Percutaneous transhepatic portography in the assessment of portal hypertension. Clinical correlations and comparison of radiographic techniques. Gastroenterology 78: 197–205
Burcharth F, Sorensen TIA, Anderson B (1980) Findings in percutaneous transhepatic portography and variceal bleeding in cirrhosis. Surg Gynecol Obstet 150: 887–890
McCormack TT, Rose JD, Smith PM, Johnson AG (1983) Perforating veins and blood flow in esophageal varices. Lancet 2: 1442–1444
Palmer ED, Brick IB (1956) Correlation between the severity of esophageal varices in portal cirrhosis and their propensity toward hemorrhage. Gastroenterology 30: 85–90
Staritz M, Poralla T, Ewe K, Meyer zum Büschenfelde K–H (1984) Ein neues Verfahren zur direkten Messung des Ösophagusvarizenblutdrukkes. Methodik and erste Untersuchungsergebnisse. Verh Dtsch Ges Inn Med 90 (im Druck)
Gertsch P, Loup P, Diserens H, Mosimann F, Mosimann R (1982) Endoscopic noninvasive manometry of esophageal varices: Prognostic significance. Am J Surg 144: 528–530
Baker LA, Smith C, Liebermann G (1959) A natural history of esophageal varices. Am J Med 26: 228–236
Dagradi AE (1972) The natural history of esophageal varices in patients with alcoholic liver cirrhosis: An endoscopic and clinical study. Am J Gastroenterol 57: 520–540
Spech HJ, Wördehoff D (1982) Klassifizierung von Ösophagusvarizen endoskopische and klinische Aspekte. Leber Magen Darm 12: 109–114
Westaby D, Macdougall BRD, Saunders JB, Williams R (1982) A study of risk factors in patients with cirrhosis and variceal bleeding. In: Westaby D, Macdougall BRD, Williams R (eds) Variceal bleeding. Pitman, London, p 36
Eckhardt VF, Grace ND (1979) Gastroesophageal reflux and bleeding esophageal varices. Gastroenterology 76: 39–42
Orloff MJ, Thomas HS (1963) Pathogenesis of esophageal varix rupture. A study based on gross and microscopic examination of the esophagus at the time of bleeding. Arch Surg 87: 301–307
Ponce J, Froufe A, DeLa Morena E, Mir J, Rayon M, Pina R, Berenguer J (1981) Morphometric study of the esophageal mucosa in cirrhotic patients with variceal bleeding. Hepatology 1: 641–646
Spence RAJ, Sloan JM, Johnston GW (1983) Oesophagitis in patients undergoing oesophageal transection for varices a histological study. Br J Surg 70: 332–334
Macdougall BR, Williams R (1983) A controlled clinical trial of cimetidine in the recurrence of variceal hemorrhage: implications about the pathogenesis of hemorrhage. Hepatology 3: 69–73
Beppu K, Inokuchi K, Koyanagi N (1981) Prediction of variceal hemorrhage by esophageal endoscopy. Gastrointest Endosc 27: 213–218
Paquet KJ (1982) Prophylactic endoscopic sclerosing treatment of the esophageal wall in varices — a prospective controlled randomized trial. Endoscopy 14: 4–5
Paquet KJ (1983) Sklerosierung zur Prophylaxe einer Ösophagusvarizenblutung. Internist 24: 81–84
Spence RAJ, Sloan JM, Johnston GW, Greenfield A (1983) Oesophageal mucosal changes in patients with varices. Gut 24: 1024–1029
Sauerbruch T, Weinzierl M, Köpcke W, Paumgartner G (1984) Longterm sclerotherapy of bleeding esophageal varices in patients with liver cirrhosis. An evaluation of mortality and rebleeding risk factors. Scand J Gastroenterol (in press)
Pugh RNH, Murray–Lyon IM, Dawson JL (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60: 646–649
Alwmark AS et al. (1982) Emergency and long–term transesophageal sclerotherapy of bleeding esophageal varices. Scand J Gastroenterol 17: 409–412
Athanasoulis CA (1980) Therapeutic applications of angiography. N Engl J Med 302: 1117–1125
Barsoum MS et al. (1982) Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices. Br J Surg 69: 76–78
Bauer JJ et al. (1974) The use of the Sengstaken–Blakemore tube for immediate control of bleeding esophageal varices. Ann Surg 179: 273–277
Baum S et al. (1971) The control of gastrointestinal bleeding by selective mesenteric arterial infusion of vasopressin. Radiology 98: 497–505
Bengmark S et al. (1979) Obliteration of esophageal varices by PTP. Ann Surg 190: 549–554
Bennet HD et al. (1952) Complications in the use of esophageal compression balloons (Sengstaken–tube). Arch Intern Med 90: 196–200
Bertrand MML et al. (1969) La sonde de Linton–Nachlas. Arch Fr Mal App Dig 58: 797–816
Bosch J et al. (1981) Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: Comparison with vasopressin. Gastroenterology 80: 518–525
Brunner G et al. (1982) Therapie blutender Ösophagusvarizen. Dtsch Med Wochenschr 107: 1791–1995
Brunswig D et al (1972) Die Behandlung der Osophagusvarizenblutung mit Linton–Nachlas–Sonde. Dtsch Med Wochenschr 97: 502–507
Brunswig D et al. (1974) Komplikationen bei der Behandlung von Ösophagusvarizenblutungen mit Ballonsonden. Therapiewoche 39: 4261–4267
Burcharth F et al. (1976) Experiences with the Linton–Nachlas and the Sengstaken–Blakemore tubes for bleeding esophageal varices. Surg Gynecol Obstet 142: 529–531
Burroughs MK et al. (1982) Randomised, controlled study of transhepatic obliteration of varices and oesophageal stapling transection in acute varical haemorrhages. In: Westaby D, MacDougal BRD, Williams R (eds). Variceal bleeding. Pitman, London, pp 199–206
Byrne WD et al. (1962) Complications associated with the use of esophageal compression ballons. Am J Surg 104: 250–254
Cello JP et al. (1982) Endoscopic sclerotherapy versus esophageal transection in child’s class C patients with variceal hemorrhage. Comparison with results of portacacal shunt: Preliminary report. Surgery 91: 333–338
Chojkier M et al. (1979) A controlled comparison of continuous intraarterial and intravenous infusions of vasopressin in hemorrhage from esophageal varices. Gastroenterology 77: 540–546
Chojkier M et al. (1980) Esophageal tamponade in the treatment of bleeding varices. Dig Dis Sci 25: 267–272
Clanet J et al. (1978) Traitement par la pitressine des hemorragies par rupture de varices oesophagiennes chez cirrhotique. Acta Gastroenterol Belg 41: 539–543
Conn HO (1958) Hazards attending the use of esophageal tamponade. N Engl J Med 259: 701–707
Conn HO et al. (1962) Multiple infusions of posterior pituitary extract in the treatment of bleeding esophageal varices. Ann Intern Med 57: 804–809
Conn HO, Simpson AJ (1967) Excessive mortality with balloon tamponade of bleeding varices. JAMA 202: 135–138
Conn HO et al. (1972) Selective intraarterial vasopressin the treatment of upper gastrointestinal hemorrhage. Gastroenterology 63: 634–645
Conn HO et al. (1975) Intraarterial vasopressin in the treatment of upper gastrointestinal hemorrhage: A prospective controlled clinical trial. Gastroenterology 68: 211–221
Cooperman AM et al. (1976) Transhepatic variceal sclerotherapy. Arch Surg 111: 609
Crafoord C et al. (1939) New surgical treatment of varicous veins of the oesophagus. Acta Otolaryngol (Stockh) 27: 422–429
Deimer E et al. (1978) Zur transhepatischen Verödung blutender Ösophagusvarizen bei der Leberzirrhose. Fortschr Röntgenstr Nuklearmed 128: 119–124–
Denck H (1977) Die endoskopische Behandlung von Osophagusvarizen. Chirurg 48: 212–218
Dostal G et al. (1981) Ergebnisse der Sklerosierungstherapie der Osophagusvarizenblutung. Med Welt 32: 106–108
Doyon D et al. (1975) Embolisation transhepatique des varices oesophagiennes. J Radiol Electrol Med Nucl 56: 917–921
Ferentzi C (1982) Technik, Indikation und Ergebnisse der prophylaktischen endoskopischen, paravasalen Osophaguswandsklerosierung. Therapiewoche 32: 1921–1923
Fleig WE et al. (1983) Emergency endoscopie sclerotherapy for bleeding esophageal varices: a prospective study in patients not responding to balloon tamponade. Gastrointest Endosc 1: 8–14
Freeman GJ et al. (1982) Controlled trial of terlipressin (glypressin) versus vasopressin in the early treatment of oesophageal varices. Lancet 1: 66–68
Freeny PC et al. (1979) Transhepatic portal venography and selective obliteration of gastrooesophageal varices using Isobutyl 2–Cyanoacrylate (Bucrylate). Dig Dis Sci 24: 321–330
Funaro AH et al. (1979) Transhepatic obliteration of esophageal varices using the stainless steel coil. Am J Roentgenol 133: 1123–1125
Gallenkamp H et al. (1981) Aspekte zur Therapie der Osophagusvarizenblutung. Med Welt 32: 393–397
Getzen LC et al. (1978) Survival following infusion of pitressin into the superior mesenteric artery to control bleeding esophageal varices in cirrhotic patients. Ann Surg 187: 337–342
Goldman ML et al. (1976) Transjugular obliteration of the gastric coronary vein. Radiology 118: 453–455
Goldman ML et al. (1978) Transcatheter vascular occlusion therapy with isobutyl 2–cyanocrylate for control of massive upper gastrointestinal bleeding. Radiology 129: 41–49
Goodale RL et al. (1982) Early survival after sclerotherapy for bleeding esophageal varices. Surg Gynecol Obstet 155: 523–528
Gow GA et al. (1960) Hemorrhage from esophageal varices. Can Med Assoc J 83: 1032–1036
Hamilton JE (1955) The management of bleeding esophageal varices associated with cirrhosis of the liver. Ann Surg 141: 637–647
Henderson JM et al. (1979) Percutaneous transhepatic occlusion for bleeding oesophageal varices. Br J Surg 66: 569–571
Hermann RE et al. (1970) Experience with the Sengstaken–Blakemore tube for bleeding esophageal varices. Surg Gynecol Obstet 130: 870–885
Hild P et al. (1982) Sklerosierungstherapie zur Behandlung der akuten Osophagusvarizenblutung. Notfallmedizin 8. 1414–1418
Hughes RW et al. (1982) Endoscopie variceal sclerosis: a one year experience. Gastrointest Endosc 28: 62–66
Joelsson B et al. (1981) Acute treatment of bleeding oesophageal varices. Scand J Gastroenterol 16: 81–85
Johanson TS et al. (1973) Re–appraisal of the Sengstaken–Blakemore balloon tamponade for bleeding esophageal varices; results in 91 patients. Scand J Gasteroenterol 8: 181–1983
Johnson WC et al. (1977) Control of bleeding varices by vasopressin. Ann Surg 186: 369–376
Johnston GW et al. (1964) Management of bleeding oesophageal varices when portal systemic shunts is inadvisable, with particular reference to the use of balloon tamponade and sclerosing injections. Ulster Med J 33: 110–118
Johnson GW et al. (1973) A review of 15 years experience in the use of sclerotherapy in the control of acute haemorrhage from oesophageal varices. Br J Surg 60: 797–800
Jorge AD (1982) Injection sclerotherapy of esophageal varices. Endoscopy 14: 115–118
Josen AS et al. (1976) Immediate endoscopie diagnosis of upper gastrointestinal bleeding, its accuracy and value in relation to associate pathology. Surgery 111: 980–986
Kapelman B et al. (1982) Endoscopie sclerotherapy as definitive treatment of esophageal varices. Gastroenterology 82: 1095–1096
Kapp F et al. (1973) Ösophaguswandsklerosierung als Therapie blutender Ösophagusvarizen bei inoperablen Patienten. Dtsch Med Wochenschr 98: 2465–2469
Kehne JH et al. (1956) The use of surgical pituitrin in the control of esophageal varix bleeding. Surgery 39: 917–925
Keller FS et al. (1981) Embolization in the treatment of bleeding gastroesophageal varices. Semin Roentgenol 16: 103–115
Kempe SG et al. (1954) Injection of sclerosing solutions in the treatment of esophageal varices. Acta Otolaryngol (Stockh) 118: 120–129
Kjaergaard J et al. (1982) Sclerotherapy of bleeding esophageal varices. Scand J Gastroenterol 17: 363–367
Kronberger OH et al. (1976) Erfahrungen mit der submukösen Sklerosierungstechnik bei Ösophagusvarizen. Leber Magen Darm 6: 38–42
Kunstlinger F et al. (1978) The obliteration of gastro–oesophageal varices by veinous route: Discussion of 22 cases. J Belg Radiol 61: 99–107
Leger L et al. (1973) Hemorragies digestives chez le cirrhotique. J Chir (Paris) 106: 45–46–
Lewis J et al. (1980) Sclerotherapy of esophageal varices. Arch Surg 115: 176–180.
Lewis JW et al. (1981) Injection sclerotherapy for control of acute variceal hemorrhage. Am J Surg 142: 592–595
Ludington LG et al. (1958) A study of 158 cases of esophageal varices. Surg Gynecol Obstet 106: 519–526
Lunderquist A et al. (1977) Follow–up of patients with portal hypertension of esophageal varices treated with percutaneous obliteration of gastric coronary vein. Radiology 122: 59–63
Macbeth R (1955) Treatment of esophageal varices in portal hypertension by means of sclerosing injections. Br Med J 2: 877–880
MacDougal BRD et al. (1982) Increased long–term survival hemorrhage using injection sclerotherapy. Lancet 1: 124–127
Magnenant P (1959) La sonde de Sengstaken–Blakemore. Rev Int Hepat 9: 541–562
Mallory A et al. (1980) Selective intra–arterial vasopressin infusion for upper gastrointestinal tract hemorrhage. Arch Surg 115: 30–32
Marubbio ATH et al. (1973) Control of variceal bleeding by superior mesenteric artery pitressin perfusions complications and indications. Dig Dis 18: 539–543
Mendez G et al. (1980) Gastrointestinal varices: Percutaneous transhepatic therapeutic embolization in 54 patients. Am J Roentgenol 135: 1045–1050
Merigan TC et al. (1960) Gastrointestinal bleeding with cirrhosis. A study of 172 episodes in 158 patients. N Engl J Med 263: 579–585
Merigan TC et al. (1962) Effect of intravenously administered posterior pituitary extract on hemorrhage from bleeding esophageal varices. A controlled evaluation. N Engl J Med 266: 134–135
Mitchell K et al. (1980) Prospective comparison of two Sengstaken tubes in the management of patients with variceal haemorrhage. Gut 21: 570–573
Moersch JJ (1947) Treatment of esophageal varices by injection of a sclerosing solution. JAMA 135: 754–757
Murray–Lyon JM et al. (1973) Treatment of bleeding oesophageal varices by infusion of vasopressin into the superior mesenteric artery. Gut 14: 59–63
Nachlas MM (1955) A new triple–lumen tube for the diagnosis and treatment of upper gastrointestinal hemorrhage. N Engl J Med 252: 720–721
Novis BH et al. (1976) Fiberoptic endoscopy and the use of the Sengstaken–Blakemore tube in acute gastrointestinal haemorrhage in patients with portal hypertension and varices. Gut 17: 258–263
Nussbaum M et al. (1974) Selective superior mesenteric arterial infusion of vasopressin during portosystemic shunt operations. Am J Surg 127: 35–39
Orloff MJ (1980) Emergency diagnosis and medical management of bleeding esophageal varices. In: Orloff MJ, Stipa S, Ziparo V (eds) Medical and surgical problems of portal hypertension. Academic Press, London New York Toronto Sydney San Francisco, pp 3–14
Palani CK et al. (1981) Endoscopie sclerotherapy in acute variceal hemorrhage. Am J Surg 141: 164–168
Paquet KJ et al. (1981) Sclerotherapy of esophageal varices. In: Papp JP (ed) Endoscopie control of gastrointestinal hemorrhage. CRC, Boca Raton, pp 44–71
Paquet KH (1982) Prophylactic endoscopie sclerosing treatment of the esophageal wall in varices.–A prospective controlled randomized trial. Endoscopy 14: 4–5
Paquet NH, Feussner H (1984) Wandsklerosierung der Speiseröhre oder Sondentamponade bei der akuten Ösophagusblutung. In Zelder O et al. (Hrsg) Experimentelle und klinische Hepatologie. Schattauer, Stuttgart New York, S 57–65
Patterson CO (1946) The injection treatment of esophageal varices. JAMA 130: 384–386
Pinel J et al. (1976) Sclerose des varices oesophagiennes. Bilan d’une experience de 10 annees. Ann Otolaryngol Chir Cerricofac 93: 245–254
Pitcher JL (1971) Safety and effectiveness of the modified Sengstaken–Blakemore tube: A prospective study. Gastroenterology 61: 291–298
Raschke E et al. (1973) Management of hemorrhage from esophageal varices using the esophagoscopic sclerosing method. Ann Surg 177: 99–102
Raptis S et al. (1979) Somatostatin not helpful in bleeding esophageal varices. N Engl Med 300: 736–737
Read AE et al. (1960) Bleeding oesophageal varices treated by oesophageal compression tube. Br Med J 1: 227–231
Reynolds TB et al. (1952) Results of the treatment of bleeding esophageal varices with balloon tamponage. Am J Med Sci 225: 500–506
Rigberg LA et al. (1977) Continuous low dose peripheral vein pitressin infusion in the control of variceal bleeding. Am J Gastroenterol 68: 481–484
Rösch J et al. (1971) Selective arterial infusions of vasoconstrictors in acute gastrointestinal bleeding. Radiology 99: 27–36
Sagar S et al. (1979) Emergency treatment of variceal haemorrhage. Br J Surg 66: 824–826
Schmidt HD et al. (1980) Ösophaguswandsklerosierung und transhepatische Verödung. Z Gastroenterol 18: 243–251
Schröder R et al. (1973) Zur Therapie der schweren Osophagusvarizenblutung. Schweiz Med Wochenschr 103: 1081–1086
Schwartz SI et al. (1959) The use of intravenous pituitrin in treatment of bleeding esophageal varices. Surgery 45: 72–80
Scott W et al. (1981) Endoscopie sclerosis of esophageal varices. Gastrointest Endosc 27: 131–132
Samson PC et al. (1942) Direct injection of esophageal varices through the esophagoscope. West J Surg Obst Gynec 50: 73–77
Shaldon S et al. (1960) The use of Vasopressin (Pitressin) in the control of bleeding from oesophageal varices. Lancet 1: 222–225
Sivak MV et al. (1980) Injection sclerosis of esophageal varices using a fiberoptic endoscope. Gastrointest Endosc 27: 52–57
Smith—Laing G et al. (1981) Role of percutaneous transhepatic obliteration of varices in the management of hemorrhage from gastroesophageal varices. Gastroenterology 80: 1031–1036
Soehendra N (1981) Fiberendoskopische Osophagusvarizenverödung. Begleittext zu einem Film, Hamburg 1981
Soehendra K et al. (1983) Sclerotherapy of oesophageal varices by means of fiberendoscopy. Clin Hepatol 29: 281–290
Spech HJ et al. (1982) Gastrointestinale Blutung: Osophagusvarizen. In: Siewert JR, Blum AL, Farthmann EH, Lankisch PG (Hrsg) Notfalltherapie. Springer, Berlin Heidelberg New York, S 120–133
Stray N et al. (1982) Injection sclerotherapy of bleeding oesophageal and gastric varices using a flexible endoscope. Acta Med Scand 211: 125–129
Takase Y et al. (1982) Injection sclerotherapy of esophageal varices for patients undergoing emergency and elective surgery. Surgery 92: 474–479
Terblanche J et al. (1981) A Five–year prospective evaluation of tamponade and sclerotherapy. Ann Surg 194: 521–530
Terblanche J et al. (1983) Failure of repeated injection sclerotherapy to improve long term survival after oesophageal variceal bleeding. Lancet 2: 1328–1332
Teres J et al. (1978) Esophageal tamponade for bleeding varices. Gastroenterology 75: 566–569
Thau A et al. (1980) Control of gastrooesophageal bleeding varices by percutaneous transhepatic portography. In: Orloff MJ, Stipa S, Ziparo V (eds) Medical and surgical problems of portal hypertension. Academic Press, London New York Toronto Sydney San Francisco, pp 33–47
Thau A, Stölzing H (1984) Ergebnisse der Sklerosierungsbehandlung. In: Zelden O et al. (Hrsg) Experimentelle und klinische Hepatologie. Schattauer, Stuttgart New York, S 17–32
Thulin L et al. (1979) Treatment of bleeding oesophageal varices with somatostatin. Acta Chir Scand 145: 395–398
Tsakiris A et al. (1964) Reduction of portal venous pressure in cirrhotic patients with bleeding from oesophageal varices, by administration of a vasopressin derivative, phenylalanine–lysine–vasopressin. Am J Med 36: 825–839
Tyden G et al. (1978) Treatment of bleeding oesophageal varices with somatostatin. N Engl J Med 299: 1466–1467
Tyden G et al. (1979) N Engl J Med 301: 46
Varela PM et al. (1973) Utilidad de la sonda–balon de Sengstaken–Blakemore. Estudio prospectivo. Rev Exp Enferm Apar Dig 39: 283–298
Viamonte M et al. (1977) Transhepatic obliteration of gastrooesophageal varices: Results in acute and nonacute bleeders. Am J Roentgenol 129: 237–241
Villanueva A, Magnenant P (1964) Resultats du traitement des hemorragies oesophagogastriques sur varices par la sonde de Sengstaken–Blakemore. Gastroenterologia (Basel) 102: 242–246
Welch CS et al. (1956) Treatment of bleeding from portal hypertension in patients with cirrhosis of the liver. N Engl Med 254: 493–496
Wells RF (1973) Management of bleeding esophageal varices in the elderly. Geriatrics: 90–93
Westaby D et al. (1983) A prospective randomized study of two sclerotherapy techniques for esophageal varices. Hepatology 3: 681–684
Widrich CH et al. (1980) Transhepatic variceal occlusion. In: Orloff MJ, Stipa S, Ziparo V (eds) Medical and surgical problems of portal hypertension. Academic Press, London New York Toronto Sydney San Francisco, pp 49–55
Wodak E (1979) Akute gastrointestinale Blutung: Resultate der endoskopischen Sklerosierung von Osophagusvarizen. Schweiz Med Wochenschr 109: 591–594
Wördehoff D et al. (1982) Konservative Therapie und Wandsklerosierung bei der Osophagusvarizenblutung. Z Gastroenterol 20: 139–144
Ayres SJ, Goff JS, Warren GH (1983) Endoskopic sclerotherapy for bleeding esophageal varices: effects and complications. Ann Intern Med 98: 900–903
Barsoum MS, Bolous FI, El–Rooby AA, Rizk–Allah MA, Ibrahim AS (1982) Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices. Br J Surg 69: 76–78
Burchell AR, Moreno AH, Panke WF, Nealon TF (1974) Hemodynamic variables and prognosis following portacval shunts. Surg Gynecol Obstet 138: 359–369
Denck H (1978) Indikation, Technik und Ergebnisse der endoskopischen Behandlung von Ösophagusvarizen. Zentralbl Chir 103: 213–220
Evans DM, Jones DB, Cleary BK, Smith PM (1982) Oesophageal varices treated by sclerotherapy: a histopathological study. Gut 23: 615–620
Galambos JT (1983) Endoscopic sclerotherapy. Ann Intern Med 98: 1009–1011
Hamm B, Altenähr E (1982) Morphologische Befunde am distalen Ösophagus nach Sklerosierung blutender Varizen. Dtsch Med Wochenschr 107: 293–298
Hansen HH (1979) Experimentelle Untersuchungen zur Wirkung sklerosierender Lösung bei der paravasalen Verödungsbehandlung. Langenbecks Arch Chir 348: 201–209
Helpap B, Bollweg L (1981) Morphological changes in the terminal oesophagus with varices, following sclerosis if the wall. Endoscopy 13: 229–233
Jackson FC, Perrin EB, Felix WR, Smith AG (1971) A clinical investigation of protacaval shunt. V. Survival analysis of the therapeutic operation. Ann Surg 174: 672–701
Johnston GW, Rodgers HW (1973) A review of 15 years’ experience in the use of sclerotherapy in the control of acute haemorrhage from oesophageal varices. Br J Surg 60: 797–800
Macdougall BR, Westaby D, Theodossi A, Dawson JL, Williams R (1982) Increased long–term survival in variceal haemorrhage using injection sclerotherapy. Lancet 1: 124–127
Mitchell KJ, Macdougall BR, Silk DBA, Williams R (1982) A prospective reappraisal of emergency endoscopy in patients with portal hypertension. Scand J Gastroenterol 17: 965–968
Paquet KJ, Oberhammer E (1978) Sclerotherapy of bleeding oesophageal varices by means of endoscopy. Endoscopy 10: 7–12
Pugh RNH, Murray–Lyon JM, Dawson JL, Pietroni MC, Williams R (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60: 645–649
Resnick RH, Iber FL, Ishihara AM, Chalmers TC, Zimmermann H, Boston Inter–Hospital Liver Group (1974) A controlled study of the therapeutic portacaval shunt. Gastroenterology 67: 843–857
Reynolds TB, Donovan AJ, Mikkelsen WP, Redeker AG, Turrill FL, Weiner JM (1981) Results of a 12–year randomized trial of portacaval shunt in patients with alcoholic liver disease and bleeding varices. Gastroenterology 80: 1031–1036
Reilly JR, Schade RR, Van Thiel DS (1984) Esophageal function after injection sclerotherapy: pathogenesis of esophageal structure. Am J Surg 147: 85–88
Rose JDR, Crane MD, Smith PM (1983) Factors affecting successful endoscopie sclerotherapy for oesophageal varices. Gut 24: 946–949
Rueff BD, Prandi D, Degos F, Sicot J, Degos JD, Sicot C, Maillard JN, Fauvert R, Benhamou JP (1976) A controlled study of therapeutic portacaval shunt in alcoholic cirrhosis. Lancet 1: 655–659
Sauerbruch T, Wirsching R, Leisner B, Weinzierl M, Pfahler M, Paumgartner G (1982) Esophageal function after sclerotherapy of bleeding varices. Scand J Gastroenterol 17: 745–751
Sauerbruch T, Weinzierl M, Köpcke W, Pfahler M, Paumgartner G (1984) Langzeit—Sklerosierungstherapie blutender Ösophagusvarizen. Dtsch Med Wochenschr 109: 709–712
Sauerbruch T, Weinzierl M, Köpcke W, Paumgartner G (1984) Long—term sclerotherapy of bleeding esophageal varices in patients with liver cirrhosis. Scand J Gastroenterol (in press)
Soehendra N, De Heer K, Kempeneers J, Frommelt L (1983) Morphological alterations ofthe esophagus after endoscopie sclerotherapy of varices. Endoscopy 15: 291–296
Soehendra N, De Heer K, Kempeneers J, Runge M (1983) Sclerotherapy of esophageal varices: acute arrest of gastrointestinal hemorrhage or long–term therapy. Endoscopy 15: 136–140
Terblanche J, Kahn D, Campbell JA, Bornman PC, Jonker MA, Wright J, Kirsch R (1983) Failure of repeated injection sclerotherapy to improve long–term survival after oesophageal variceal bleeding. Lancet 2: 1328–1332
Westaby D, Melia WM, Macdougall BR, Hegarty JE, Williams R (1984) Injection sclerotherapy for oesophageal varices: a prospective randomised trial of different treatment schedules. Gut 25: 129–132
Yassin YM, Sherif SM (1983) Randomized controlled trial of injection sclerotherapy for bleeding oesophageal varices — an interim report. Br J Surg 70: 20–22
Arthur MPJ, Tanner AR, Patel C, George CF, Wright R (1982) Portal hypertension, propranolol, and hepatic encephalopathy. Lancet 2: 879–880
Bataille C, Bercoff E, Pariente EA, Valla D, Lebrec D (1984) Effects of propranolol on renal blood flow and renal function in patients with cirrhosis. Gastroenterology 86: 129–133
Bützow GH, Remmecke J, Roose HJ (1982) Cardioselektive oder nichtselektive ß–Blockade bei portaler Hypertension? Eine prospektive Vegleichsstudie mit Metoprolol and Propranolol. Z Gastroenterol 20: 519
Bützow GH, Remmecke J, Bräuer A (1982) Metoprolol in portal hypertension. A controlled study. Klin Wochenschr 60: 1311–1314
Burroughs AK, Jenkins WJ, Sherlock S, Dunk A, Walt RP, Osuafor TOK, Mackie S, Dick R (1983) Controlled trial of propranolol for prevention of recurrent variceal hemorrhage in patients with cirrhosis. N Engl J Med 309: 1539–1542
Hillon P, Lebrec D, Munoz C, Jungers M, Goldfarb G, Benhamou JP (1982) Comparison of the effects of a cardioselective and a nonselective ß–blocker on portal hypertension in patients with cirrhosis. Hepatology 2: 528–531
Lebrec D, Nouel O, Bernuau J, Boygues M, Rueff B, Benhamou JP (1981) Propranolol in prevention of recurrent gastrointestinal bleeding in cirrhotic patients. Lancet 1: 920–921
Lebrec D, Nouel O, Corbic M, Benhamou JP (1980) Propranolol–a medical treatment for portal hypertension? Lancet 2: 180–182
Lebrec D, Poynard T, Hillon P, Benhamou JP (1981) Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis. A controlled study. N Engl J Med 305: 1371–1374
Menghini G, (1983) Letter. Hepatology 3: 466
Mills PR, Rae AP, Farah DA, Russel RI, Lorimer AR, Carter DC (1984) Comparison of three adrenoreceptor blocking agents in patients with cirrhosis and portal hypertension. Gut 25: 73–78
Reding P (1982) Risk of hepatic encephalopathy in patients taking propranolol for portal hypertension. Lancet 2: 550
Sögaard PE (1981) Propranolol in portal hypertension. Lancet 1: 1204
Tarver D, Walt RP, Dunk AA, Jenkins WJ, Sherlock S (1983) Precipitation of hepatic encephalopathy by propranolol in cirrhosis. Br Med J 287: 585
Van Buuren HR, Van der Velden PC, Koorevar G, Silberbusch J (1982) Propranolol increases arterial ammonia in liver cirrhosis. Lancet 2: 951–952
Westaby D, Bihari DJ, Gimson AES, Crossley IR, Williams R (1984) Selective and non–selective beta receptor blockade in the reduction of portal pressure in patients with cirrhosis and portal hypertension. Gut 25: 121–124
Westaby D, Macdougall BRD, Melia WM, Williams R (1983) Comparison of oral metoprolol and injection sclerotherapy for long–term management of variceal bleeding in cirrhosis. Gut 24: A459–505, F28.
Wilkinson SP (1980) Propranolol and portal hypertension in cirrhosis. Lancet 2: 429
Barsoum MS et al. (1982) The complications of injection sclerotherapy of bleeding esophageal varices. Br J Surg 69: 79–81
Belghitti J, Grenier P, Noul O, Nahum H, Fekete F (1981) Long term loss of Warren’s shunt selectivity. Arch Surg 116: 1121–1124
Burchell AR, Moreno AH, Panke WF, Nealon TF (1976) Hepatic artery flow improvement after portacaval shunt. A single hemodynamic clinical correlates. Ann Surg 184: 289–302
Burroughs AK, Bass NM, Osborne D, Dick R, Hobbs KF, Sherlock S (1983) Randomised, controlled study of transhepatic obliteration of varices and oesophageal stapling transection in uncontrolled variceal hemorrhage. Liver 3: 122–128
Busuttil RW, Brin Barbara, Tompkins RKT (1979) Matched controlled study of distal splenorenal and portocaval shunts in the treatment of bleeding esophageal varices. Am J Surg 138: 62–67
Dennis MA, Monson RC, O’Leary JP (1978) Interposition mesocaval shunt: A less than ideal procedure. Am Surg Nov: 734–738
Galambos JT, Millikan WJ, Henderson JM, Smith RB, Warren WD (1983) Ten years of shunt surgery: The current status of the selective distal splenorenal shunt. In: Variceal bleeding. London
Greiner L, Schubert E, Franken FH (1983) Koinzidenz von chronischer Pankreatitis and Leberzirrhose bei Alkoholabusus. Eine röntgen–and histomorphologische Studie. Z Gastroenterol 21: 526–532
Henderson JM, Millikan WJ, Wright–Bacon Lisa, Kutner MH, Warren WD (1983) Hemodynamic differences between alcoholic and nonalcoholic cirrhotics following distal splenorenal shunt — Effect on survival? Ann Surg 198: 325–334
Hirner A, Häring R, Vosberg W(1984) Abgrenzung der semiinvasiven (endoskopischen) zu den chirurgischen (Notshunt) Maßnahmen. In: Die Ösophagusvarizenblutung, TM—Verlag, Bad Oeynhausen
Hoffmann J (1983) Stapler transection of the oesophagus for bleeding oesophageal varices. Scand J Gastroenterol 18: 707–711
Hottenroth C, Böttcher W, Maul FD, Wildgrube PH, Förster HD, Encke A (1983) Diagnostische transumbilicale Shunt–Simulation als Indikationshilfe zum portosystemischen Shunt. Chirurg 54: 149–156
Kieninger G (1980) Der Warren–Shunt — eine neue Perspektive in der Chirurgie des Pfortaderhochdrucks. Med Welt 31: Heft 12
Maillard J–N, Flamant YM, Hay JM, Chandler JG (1979) Selectivity of the distal splenorenal shunt. Surgery 86: 663–671
Maillard J–N (1983) The French experience with shunt procedures. In: Variceal bleeding. London
Manegold BC, Weber JC (1982) Paravaricöse Sklerosierungstherapie. In: Notfalltherapie. Springer, Berlin Heidelberg New York
Mir J, Ponce J, Morena E, Juan M, Garrigues V, Pina R, Berenguer J (1982) Esophageal transsection and paraesophagogastric devascularization performed as an emergency measure for uncontrolled variceal bleeding. Surg Gynecol Obstet 155: 868–872
Mühe E (1981) Up–dated surgical strategies in portal hypertension. Acta Hepatogastroenterol 28: 125–127
Orloff MJ, Bell RH, Hyde PV, Scivolocki WP (1980) Long–term results of emergency portacaval shunt for bleeding esophageal varices in unselected patients with alcoholic cirrhosis. Ann Surg 192: 325–340
Palani CK, Abuabara S, Kraft AR, Jonasson Olga (1981) Endoscopic sclerotherapy in acute variceal hemorrhage. Am J Surg 141: 164–168
Paquet KF, Kalk HF, Feussner H (1983) Endoskopisch–chirurgische Therapie der Oesophagusvarizen. Therapiewoche 33: 1776–1788
Reilly JJ, Schade RR, Roh MS, van Thiel DH (1982) Esophageal varices sclerosis. Surg Gynecol Obstet 155: 497–502
Resnick RH, Iber FL, Ishihara AM, Chalmers TC, Hyman Zimmermann (BILG) (1974) A controlled study of the therapeutic portacaval shunt. Gastroenterology 67: 843–857
Reynolds TB, Donovan AJ, Mikkelsen WP, Redeker AG, Turrill FL, Weiner JM (1981) Results of a 12–year randomized trial of portacaval shunt in patients with alcoholic liver disease and bleeding varices. Gastroenterology 80: 1005–1011
Rikkers L, Rudman D, Galambos JT, Fulenwider JT, Millikan WJ, Kutner, M, Smith RB, Salamn AA, Jones PJ, Warren WD (1978) A randomized controlled trial of the distal splenorenal shunt. Ann Surg 188: 271–282
Siewert JR, Becker HD (1979) Transmurale Varizenumstechung und Fundoplicatio als Notoperation der akuten Oesophagusvarizenblutung. Chirurg 50: 82–86
Sugiura M, Futagawa S (1977) Further evaluation of the sugiura procedure in the treatment of esophageal varices. Arch Surg 112: 1317–1321
Talman AE, Johns TNP, Regan WW (1983) A 25–year experience with total portosystemic shunts and reappraisal of colon exclusion. Ann Surg 197: 566–573
Teschke R (1983) Hohe Inzidenzrate von chronischer Pankreatitis und Leberzirrhose bei chronischem Alkoholabusus? Z Gastroenterol 21: 533–535
Thompson BW, Casali RE, Read RC, Campbell GS (1978) Results of interposition “H” grafts for portal hypertension. Ann Surg 187: 515–522
Warren WD (1983) Control of variceal bleeding. Reassessment of rationale. Am J Surg 145: 8–16
Wexler MJ (1980) Treatment of bleeding esophageal rices by transabdominal esophageal transection with the EEA stapling instrument. Surgery 88: 406–416
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Paumgartner, G., Egberts, EH., Sauerbruch, T., Bützow, G.H., Siewert, J.R., Feussner, H. (1984). Symposium B. In: 90. Kongreß. Verhandlungen der Deutschen Gesellschaft für Innere Medizin, vol 90. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-85457-6_11
Download citation
DOI: https://doi.org/10.1007/978-3-642-85457-6_11
Publisher Name: J.F. Bergmann-Verlag, Munich
Print ISBN: 978-3-8070-0342-9
Online ISBN: 978-3-642-85457-6
eBook Packages: Springer Book Archive