Effect of Intravenous Polyunsaturated Phosphatidyl Choline in Experimental Atherosclerosis

  • A. N. Howard
  • J. Patelski
Part of the Verhandlungen der Deutschen Gesellschaft für Innere Medizin book series (VDGINNERE, volume 78)


The relationship between the metabolism of phospholipids, glycerides and cholesterol esters in the arterial wall and the development of atherosclerosis has become a subject of considerable interest in recent years. We have shown [1] that in experimental atherosclerosis in rats and in rabbits, there is an increase in lipase and phospholipase activity and a decrease in cholesterol esterase activity in the arterial wall and it is suggested that these might be contributing factors in the production of the arterial lesions.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1972

Authors and Affiliations

  • A. N. Howard
    • 1
    • 2
  • J. Patelski
    • 1
    • 2
  1. 1.Department of Investigative MedicineUniv. of CambridgeUK
  2. 2.Medical AcademyPoznanPoland

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