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Effect of Intravenous Polyunsaturated Phosphatidyl Choline in Experimental Atherosclerosis

  • Conference paper
Achtundsiebzigster Kongress

Part of the book series: Verhandlungen der Deutschen Gesellschaft für Innere Medizin ((VDGINNERE,volume 78))

Abstract

The relationship between the metabolism of phospholipids, glycerides and cholesterol esters in the arterial wall and the development of atherosclerosis has become a subject of considerable interest in recent years. We have shown [1] that in experimental atherosclerosis in rats and in rabbits, there is an increase in lipase and phospholipase activity and a decrease in cholesterol esterase activity in the arterial wall and it is suggested that these might be contributing factors in the production of the arterial lesions.

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References

  1. Patelski, J., Bowyer, D. E., Howard, A. N., Gresham, G. A.: J. Atheroscler. Res. 8, 221 (1968).

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  2. Schrade, W., Bohle, E., Biegler, R.: In: Drugs affecting lipid metabolism, p. 454 ( Garattini, S., Paoletti, R., Eds.). Amsterdam: Elsevier 1961.

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  3. Patelski, J., Bowyer, D. E., Howard, A. N., Jenrings, I. W., Thorne, C. J. R., Gresham, G. A.: Atherosclerosis 12, 41 (1970).

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  4. Howard, A. N., Patelski, J., Bowyer, D. E., Gresham, G. A.: Atherosclerosis 14, 17 (1971).

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  5. Howard, A. N.: From: Proceedings of the 1968 Deuel Conference on The Turnover of Lipids and Lipoproteins, p. 171 (Cowgill, G., Estrich, D. L., Wood, P. D., Eds.). Washington: U.S. Department of Health, Education and Welfare 1968.

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  6. Rothblat, G. H., Hartzell, R., Mialhe, R., Kritchevsky, D. (Eds.), Rothblat, G., Kritchevsky, D., p. 129. Philadelphia: Wistar Institute Press 1967.

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Author information

Authors and Affiliations

  1. Department of Investigative Medicine, Univ. of Cambridge, UK

    A. N. Howard & J. Patelski

  2. Medical Academy, Poznan, Poland

    A. N. Howard & J. Patelski

Authors
  1. A. N. Howard
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  2. J. Patelski
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Editor information

Editors and Affiliations

  1. Wiesbaden, Deutschland

    B. Schlegel

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© 1972 Springer-Verlag Berlin Heidelberg

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Howard, A.N., Patelski, J. (1972). Effect of Intravenous Polyunsaturated Phosphatidyl Choline in Experimental Atherosclerosis. In: Schlegel, B. (eds) Achtundsiebzigster Kongress. Verhandlungen der Deutschen Gesellschaft für Innere Medizin, vol 78. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-85448-4_287

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  • DOI: https://doi.org/10.1007/978-3-642-85448-4_287

  • Publisher Name: J.F. Bergmann-Verlag, Munich

  • Print ISBN: 978-3-8070-0287-3

  • Online ISBN: 978-3-642-85448-4

  • eBook Packages: Springer Book Archive

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