Abstract
Kaufmann has already summarized some important historical data on the development of knowledge about the “nutritive value” of proteins [16]. The documentation of this knowledge began 200 years ago with the first description of nitrogen, an element which scientists initially regarded as “azote,” meaning lifeless, until it was recognized that, on the contrary, nitrogen is essential to life.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Brantl V, Teschemacher H, Bläsig J, Henschen A, Lottspeich F (1979) Novel opioid peptides derived from casein (ß-casomorphins). I. Isolation from bovine casein peptone. Hoppe-Seyler’s Z Physiol Chem 360: 1211–1216
Brantl V, Teschemacher H, Bläsig J, Henschen A, Lottspeich F (1981) Opioid activities of ß-casomorphin. Life Sci 28: 1903–1909
Brantl V, Pfeiffer A, Herz A, Henschen A, Lottspeich F (1982) Antinociceptive potencies of ß-casomorphin analogs as compared to their affinities towards p and a opiate receptor sites in brain and periphery. Peptides 3: 793–797
Brantl V, Schmitzler G, Daniel H (1988) ß-Casomorphine: Opioide aus Casein als Modulatoren gastrointestinaler Funktionen. 2. Effekte auf intestinale Sekretionsprozesse. Ernährungsumschau 35: 160
Braunitzer G, Chen R, Schrank B, Stangj A (1973) Die Sequenzanalyse des ß-Lactoglobulin. Hoppe-Seyler’s Z Physiol Chem 354: 867–878
Chang KJ, Killian A, Hazum E, Cuatrecasas P (1981) Morphiceptin: A potent and specific agonist for morphine (y) receptors. Science 212: 75–77
Chang KJ, Cuatrecasas JP, Wei ET, Chang JK (1982) Analgesic activity of intracerebroventricular administration of morphiceptin and ß-casomorphins: Correlation with the morphine (y) receptor binding affinity. Life Sci 30: 1547–1551
Chang KJ, Su YF, Brent DA, Chang JK (1985) Isolation of a specific y-opiate receptor peptide, morphiceptin, from an enzymatic digest of milk proteins. J Biol Chem 260: 9706–9712
Chiba H, Yoshikawa M (1986) Biologically functional peptides from food proteins: New opioid peptides from milk proteins. In: Feeney RE, Whitaker JR (eds) Protein tailoring for food and medical uses. Marcel Dekker, New York and Basel, pp 123–153
Daniel H, Vohwinkel M, Brantl V (1988) ß-Casomorphine: Opioide aus Casein als Modulatoren gastrointestinaler Funktionen. 1. Effekte auf die gastrointestinale Motilität. Ernährungsumschau 35: 160
Findlay JBC, Brew K (1972) The complete amino acid sequence of human a-lactalbumin. Eur J Biochem 27: 65–86
Frister H, Hagemeister H, Meisel H, Schlimme E (1987) Postprandiale intestinale Proteolyse. In: Forschungsbericht Bundesanstalt für Milchforschung Kiel (EWG Nr. 282/84–26.1). Auffindung von neuen Maßstäben zur Bewertung von Milcheiweiß im Vergleich zu pflanzlichem Eiweiß, S 2–29
Greenberg R, Groves ML, Dower HJ (1984) Human ß-casein: Amino acid sequence and identification of phosphorylation sites. J Biol Chem 259: 5132–5138
Hagemeister H, Pfeuffer M, Scholz-Ahrens K-E, Barth C (1987) Metabolische Effekte. In: Forschungsbericht Bundesanstalt für Milchforschung Kiel (EWG Nr. 282/84–26.1) Auffindung von neuen Maßstäben zur Bewertung von Milcheiweiß im Vergleich zu pflanzlichem Eiweiß, S 34–56
Henschen A, Lottspeich F, Brantl V, Teschemacher H (1979) Novel opioid peptides derived from casein (f3-casomorphins). II. Structure of active components from bovine casein peptone. Hoppe-Seyler’s Z Physiol Chem 360: 1217–1224
Kaufmann W (1983) Role of milk proteins in human nutrition. Kieler Milchwirtschaftliche Forschungsberichte 35: 241–245
Lottspeich F, Henschen A, Brantl V, Teschemacher H (1980) Novel opioid peptides derived from casein (ß-casomorphin) III. Synthetic peptides corresponding to components from bovine casein peptone. Hoppe-Seyler’s Z Physiol Chem 361: 1835–1839
Loukas S, Varoucha D, Zioudrou C, Streaty RA, Klee WA (1983) Opioid activities and structures of a-casein-derived exorphins. Biochemistry 22: 4567–4573
Meisel H (1986) Chemical characterization and opioid activity of an exorphin isolated from in vivo digests of casein. FEBS Lett 196: 223–227
Meisel H, Hagemeister H (1987) Postprandiale Proteolyse von Casein and Sojaprotein. Milchwissenschaft 42: 153–158
Meisel H, Frister H (1988) Chemical characterization of a phospho-peptide isolated from in vivo digests of casein. In: Barth C, Schlimme E (eds) Milk proteins: Structural, functional, technological and clinical aspects. Steinkopff, Darmstadt, Springer, New York, pp 150–154
Mercier JC, Brignon G, Ribadeau-Dumas B (1973) Structure primaire de la caséine B bovine. Séquence complète. Eur J Biochem 35: 222–235
Morley JE, Levine AS, Yamada T, Gebhard RK, Prigge WF, Shafer RB, Goetz FC, Silvis SE (1983) Effect of exorphins on gastrointestinal function, hormonal release, and appetite. Gastroenterology 84: 1517–1523
Parker F, Migliore-Samour D, Floc’h F, Zerial A, Werner GH, Jollès J, Casaretto M, Zahn H, Jollès P (1984) Immunostimulating hexapeptide from human casein: amino acid sequence, synthesis and biological properties. Eur J Biochem 145: 677–682
Schusdziarra V, Schick R, de la Fuente A, Holland A, Brantl V, Pfeiffer EF (1983) Effect of ß-casomorphins on somastatin release in dogs. Endocrinology 112: 1948–1951
Svedberg J, de Haas J, Leimenstoll G, Paul F, Teschemacher H (1985) Demonstration of ß-casomorphin immunoreactive materials in in vitro digests of bovine milk and in small intestine contents after bovine milk ingestion in adult humans. Peptides 6: 825–830
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt
About this chapter
Cite this chapter
Schlimme, E., Meisel, H., Frister, H. (1989). Bioactive Sequences in Milk Proteins. In: Barth, C.A., Schlimme, E. (eds) Milk Proteins. Steinkopff. https://doi.org/10.1007/978-3-642-85373-9_20
Download citation
DOI: https://doi.org/10.1007/978-3-642-85373-9_20
Publisher Name: Steinkopff
Print ISBN: 978-3-642-85375-3
Online ISBN: 978-3-642-85373-9
eBook Packages: Springer Book Archive