Comparison of verapamil and bepridil in the therapy of familiar cardiomyopathy of the Syrian hamster

  • B. Kunkel
  • U. Hofmann
  • M. Mutschler
Conference paper


The effect of verapamil on the cardiomyopathic hamster is wellknown from the basic works of Loßnitzer (6–9). It is not known, however, whether different calcium-antagonists have the same cardioprotective potency. In this study we analyzed the effect of bepridil, on the cardiomyopathic hamster. Bepridil is shown to be a calcium antagonistic drug (10) with documented antianginal (1) in humans efficacy.


Hypertrophic Cardiomyopathy Necrotic Lesion Cell Necrosis Syrian Hamster Myocardial Necrosis 
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Copyright information

© Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt 1988

Authors and Affiliations

  • B. Kunkel
    • 1
    • 2
    • 3
  • U. Hofmann
    • 1
    • 2
  • M. Mutschler
    • 1
    • 2
  1. 1.Medizinische PoliklinikUniversität ErlangenGermany
  2. 2.Institut für PharmakologieUniversität FrankfurtGermany
  3. 3.Medizinische PoliklinikUniversität ErlangenErlangenGermany

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