Summary
Left ventricular hypertrophy of about 40 % was produced in rats by narrowing one renal artery (Goldblatt II) and of about 6 % by swimming-training for 2 hours a day for 14 weeks. The dynamics of the hypertrophied ventricles were investigated by means of the isovolumic systolic and diastolic pressure-volume relations, the stress development during afterloaded and isovolumic contractions, and the force-velocity relation. The following results were obtained: The performance of the whole hypertrophied ventricle is increased. The developed stress and the maximum rate of stress development are enhanced, probably as a consequence of the increased density of the contractile proteins. The maximum shortening velocity can be reduced at the same time.
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© 1977 Dr. Dietrich Steinkopff Verlag, Darmstadt
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Kissling, G., Wendt-Gallitelli, M.F. (1977). Dynamics of the hypertrophied left ventricle in the rat. Effects of physical training and chronic pressure load. In: Jacob, R. (eds) The Hypertrophied Heart. Steinkopff. https://doi.org/10.1007/978-3-642-85299-2_14
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DOI: https://doi.org/10.1007/978-3-642-85299-2_14
Publisher Name: Steinkopff
Print ISBN: 978-3-7985-0482-0
Online ISBN: 978-3-642-85299-2
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