Summary
In order to improve the therapeutic results of the ischemic syndrome of the lower limb, we carried out a retrospective follow-up of 344 patients. Acute arterial occlusion was due to an embolic event in 46.4% and to acute thrombosis in 32.7%; in 20.9% the cause could not be defined. In 29% of the embolic and in 41% of the thrombotic occlusions, efficient therapy was started more than 12 h after the acute onset of symptoms. In 67% an indirect transfemoral thrombembolectomy was performed. This result could be further improved by using modern therapeutic methods (thrombolytic treatment, combined medical and surgical treatment).
Zusammenfassung
Unter dem speziellen Gesichtspunkt der Verbesserung der Behandlungsergebnisse des akuten Ischämie-Syndroms der unteren Extremitäten erfolgte eine retrospektive Analyse von 344 Patienten. Eine arterielle Embolie lag in 46,4%, eine akute Thrombose in 32,7%, den akuten Verschlüssen zugrunde. In 20,9% war eine eindeutige Zuordnung der Verschlußursache nicht möglich. Das Zeitintervall zwischen Symptom und Beginn der Therapie betrug bei den Embolien in 29% und bei den Thrombosen in 41% mehr als zwölf Stunden. In 67% wurde eine transfemorale indirekte Thrombembolektomie durchgeführt. Durch den Einsatz neuerer risikoarmer Behandlungsmethoden (Aspirationsembolektomie, Lyse und PTA etc.) läßt sich das Ergebnis weiter verbessern.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Berguer R, Feldmann Al (1982) Infected Groin Aneurysms from Heroin Addiction. In: Bergan JJ, Yao JST (Eds) Aneurysms Diagnosis and Treatment Grune & Stratton
Patel KR, Semel L, Clauss RH (1988) Routine revascularization with resection of infected femoral pseudoaneurysms from substance abuse. Journal of Vascular Surgery, Volume 8, No 3: 321–328
Reddy DJ, Smith RF, Elliot JP, Haddad GK, Wanek EA (1986) Infected femoral artery false aneurysms in drug addicts: Evolution of selective vascular reconstruction. Journal of Vascular Surgery, Volume 3, No 5: 718–724
Zühlke HV, Harnoss B-M, Lorenz EPM (1994) Septische Gefäßchirurgie, Blackwell Wissenschaftsverlag, 128–129
Amiral J, Bridey F, Dreyfuss M, Vissac AM, Fressinaud E, Wolf M, Meyer D (1992) Platelet Factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 68: 95–96
Arzneimittelkommission der deutschen Ärzteschaft (1994) Unerwünschte Arzneimittelwirkungen durch fraktionierte and unfraktionierte Heparine. Dt Ärzteblatt 24: B1293 — B1294
Collins R, Scrimgeour A, Yusuf S, Peto R (1988) Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. N Engl J Med 318: 1162–1173
Greinacher A, Mueller-Eckhardt C (1991) Diagnostik der Heparin-assoziierten Thrombozytopenie. DMW 116: 1479–1482
Greinacher A, Pötzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C (1994) Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost 71: 247–251
Greinacher A, Liebenhoff U, Kiefel V, Presek P, Mueller-Eckhardt C (1994) Heparin-associated thrombocytopenia. The effects of various intravenous IgG preparations on antibody mediated platelet activation — a possible new indication for high dose i.v. IgG. Thromb Haemost 71: 641–645
Koster T, Rosendaal FR, de Ronde H, Briet E, Vandenbroucke JP, Bertina RM (1993) Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 342: 1500–1506
Laster J, Cikrit D, Walker N, Silver D (1987) The heparin-induced thrombocytopenia syndrome: An update. Surgery 102: 763–770
Leyvraz P, Bachmann F, Bohnet J, Breyer HG, Estoppey D, Haas S, Hochreiter J, Jabujek H, Mair J, Sorensen R (1992) Thromboembolic prophylaxis in total hip replacement: a comparison between the low molecular weight heparinoid Lomoparan and heparin-dihydroergotamine. Br J Surg 79: 911–914
Matsuo T, Kario K, Chikahira Y, Nakao K, Yamada T (1992) Treatment of heparin-induced thrombocytopenia by use of argotroban, a synthetic thrombin inhibitor. Br J Haematol 82: 627–629
Streicher H-J, Kußmann J, Koppenhagen K, Häring R, Theiss W, Adolf J, Haas S, Reilmann H, Tscherne H, Siewert JR (1988) Thromboembolie-Prophylaxe in der Chirurgie — heute obligat? Langenbecks Arch Chir 373: 136–140
Warkentin TE, Hayward CPM, Boshkov LK, Santos AV, Sheppard JAI, Bode AP, Kelton JG (1994) Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood 84:3691 —3699
Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, Kelton JG (1994) A prospective study of heparin-induced thrombocytopenia: unfractionated heparin compared with low-molecular-weight heparin. Blood 84: 188a
Allenberg JR, Lehnert T (1993) Die asymptomatische Karotisstenose: Besteht eine Indikation zur Operation? Chirurg 64: 252
Chambers BR, Norris JW (1986) Outcome in patients with asymptomatic carotid bruits. N Engl J Med 315: 860
Hohlbach G, Meffert R (1995) Nutzen-Risiko-Abwägung der operativen Behandlung asymptomatischer Karotisstenosen. Zentrbl Chir (im Druck)
Norris JW, Zhu CZ, Bornstein NM, Chambers BR (1991) Vascular risk of asymptomatic carotid stenosis. Stroke 22: 1485
Street DL, O’Brien MS, Ricotta JJ, Ekholm SE, Ouriel K, Green RM, DeWeese JA (1988) Observation on cerebral computed tomography in patients having carotid endarterectomy. J Vasc Surg 7: 798
Winslow CM, Solomon DH, Chassin MR, Koscoff J, Merrick NJ, Brook RH (1988) The appropriateness of carotid endarterectomy. N Engl J Med 318: 721–727
Warlow C: MRC European Carotid Surgery Trial; interim results for symptomatic patients with severe (70–99%) or with mild (0–29%) carotid stenosis. The Lancet 337: 1235–1243
Taylor DW, Barnett HJM: Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis. New Engl J Med 325: 445–453
Hobson RW, Weiss DG, Fields WS et al.: Efficacy of Carotid Endarterectomy for Asymptomatic Carotid Stenosis. New Engl J Med 328: 221–227
Cragg AH, DeJong S, Barnhart W, Landers SK, Smith TP (1993) Nitinol intravascular stent: results of preclinical evaluation. Radiology 189: 775–778
Steckmeier B, Küffer G, Schmölder A, Huber R, Reininger C, Spengel FA (1991) Adjuvante Angioplastie bei simultaner gefäßchirurgischer Rekonstruktion. Angio 13: 77–88
Allenberg J-R, Maeder N, Meybier H (1989) Chronisch arterielle Verschlußkrankheit im FemoralisPoplitea-Bereich. Chirurg 60: 322–329
Currie JC, Wakeley CJ, Cole SEA (1994) Femoropopliteal angioplasty for severe limb ischaemia. BrJSurg81: 191–193
Lorentzen JE, Nielsen OM, Roder OC, Schroeder TV (1993) A prospective study of 698 femoro-infrapopliteal in-situ vein and PTFE bypass procedures. VASA Supplement 42: 30–32
Roth F-J, Behrmann C, Grün B, Rieser R, Roth SP, Scheffler A (1992) Fortschritte arterieller Rekonstruktion an Ober-und Unterschenkel — Perkutane transluminale Verfahren. Langenbecks Arch Chir Suppl (Kongreßbericht): 452–458
Stein U, Reichardt M, Wagner E (1994) Prognostische Kriterien für die initiale Erfolgsrate bei PTA und Katheterthrombolyse. VASA 23: 10–14
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Dörrler, J. et al. (1995). Akute Gefäßverschlüsse — interdisziplinäres Therapiespektrum. In: Hartel, W. (eds) Qualitätssicherung durch Zusammenarbeit in der Chirurgie. Langenbecks Archiv für Chirurgie, vol 1995. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85235-0_39
Download citation
DOI: https://doi.org/10.1007/978-3-642-85235-0_39
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-60425-9
Online ISBN: 978-3-642-85235-0
eBook Packages: Springer Book Archive