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Detection of Silicone Migration and Biodegradation with NMR

  • L. Garrido
  • A. Bogdanova
  • L. L. Cheng
  • B. Pfleiderer
  • E. Tokareva
  • J. L. Ackerman
  • T. J. Brady
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 210)

Abstract

Silicones, generic name of synthetic polymers with a backbone of SiO bonds and organic side groups (aliphatic and/or aromatic), are among the most widely used materials for biomedical purposes [1]. In particular, it is estimated that about 1.5 million silicone gel-filled breast prosthesis are presently implanted in the U.S. for the purpose of reconstruction and augmentation mammaplasty. Although silicones have been assumed to be stable, their benign nature has been questioned recently, and in April 1992 the Food and Drug Administration (FDA) severely restricted the use of silicone gel-filled prostheses for breast augmentation arguing that the risks have not been adequately defined [2].

Keywords

Nuclear Magnetic Resonance Nuclear Magnetic Resonance Spectroscopy Breast Implant Silicone Implant Silicone Breast Implant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • L. Garrido
    • 1
  • A. Bogdanova
    • 1
  • L. L. Cheng
    • 1
  • B. Pfleiderer
    • 1
  • E. Tokareva
    • 1
  • J. L. Ackerman
    • 1
  • T. J. Brady
    • 1
  1. 1.NMR Center, Department of RadiologyMassachusetts General Hospital and Harvard Medical SchoolCharlestownUSA

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