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Systematrophien

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Pathologie

Zusammenfassung

Die ätiologische Klärung einiger Krankheiten führte dazu, diese nicht mehr unter die Systematrophien, sondern unter andere Krankheitsgruppen zu subsumieren, so z.B. die Gerstmann-Sträussler-Krankheit unter die Prion-Enzephalopathien und die Refsum-Krankheit unter die Enzymdefekte des Phytanstoffwechsels.

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Literatur

  1. Caine DB (ed) (1993) Neurodegenerative diseases. Saunders, London

    Google Scholar 

  2. Cervós-Navarro L(1991) Degenerative Erkrankungen des Zentralen Nervensystems. In: Doerr W, Seifert G (Hrsg) Spezielle Pathologische Anatomie, Bd 131V Springer, Berlin Heidelberg New York Tokio, S 463–897

    Google Scholar 

  3. Harper PS (ed) (1991) Huntington’s disease. Saunders, London

    Google Scholar 

  4. Litvan I, Agid Y (eds) (1992) Progressive supranuclear palsy. Clinical and research approaches. Oxford Univ Press, New York

    Google Scholar 

  5. Narabayashi H, Nagatsu T, Yanagisawa N, Mizuno Y (1993) Parkinson’s disease. Advances in neurology, vol 60. Raven, New York

    Google Scholar 

  6. Vinken PL, Bruyn GW, Klawans HL (eds) (1991) Handbook of clinical neurology, vol 60, revised series 16: Hereditary neuropathies and spinocerebellar atrophies. Elsevier, Amsterdam

    Google Scholar 

  7. Vinken PL, Bruyn GW, Klawans HL, De Jong LMBV (eds) (1991) Handbook of clinical neurology, vol 59, revised series 15: Diseases of the motor system. Elsevier, Amsterdam

    Google Scholar 

  8. Abe H, Yagishita S, Amano N et al. (1992) Argyrophilic glial intracytoplasmic inclusions in multiple system atrophy: immunocytochemical and ultrastructural study. Acta Neuropathol 84: 273–277

    PubMed  CAS  Google Scholar 

  9. Albin RL, Gilman S (1990) Autoradiographic localization of inhibitory and excitatory amino acid neurotransmitter receptors in human normal and olivopontocerebellar atrophy cerebellar cortex. Brain Res 522: 37–45

    PubMed  CAS  Google Scholar 

  10. Albin RL, Young AB, Penney JB (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci 12: 366–375

    PubMed  CAS  Google Scholar 

  11. Appel SH (1993) Excitotoxic neuronal cell death in amyotrophic lateral sclerosis. Trends Neurosci 16: 3–5

    PubMed  CAS  Google Scholar 

  12. Bancher C, Lassmann H, Budka H et al. (1987) Neurofibrillary tangles in Alzheimer’s disease and progressive supranuclear palsy: antigenic similarities and differences. Acta Neuropathol 74: 39–46

    PubMed  CAS  Google Scholar 

  13. Bancher C, Lassmann H, Budka H et al. (1989) An antigenic profile of Lewy bodies: immunocytochemical indication for protein phosphorylation and ubiquitination. J Neuropathol Exp Neurol 48: 81–93

    PubMed  CAS  Google Scholar 

  14. Beal MF, Hyman BT, Koroshetz W (1993) Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? Trends Neurosci 16: 125–131

    PubMed  CAS  Google Scholar 

  15. Bergmann M, Schmidtke K, Danek A, Gullotta F, Mehraein P (1990) Striato-nigrale Degeneration (SND): eine Multisystematrophie? Schweiz Arch Neurol Psychiatr 141: 389–405

    PubMed  CAS  Google Scholar 

  16. Braak H, Braak E (1992) Allocortical involvement in Huntington’s disease. Neuropathol Appl Neurobiol 18: 539–547

    PubMed  CAS  Google Scholar 

  17. Chokroverty S, Nicklas W, Miller DC et al. (1990) Multiple system degeneration with glutamate dehydrogenase deficiency: pathology and biochemistry. J Neurol Neurosurg Psychiatry 53: 1099–1101

    PubMed  CAS  Google Scholar 

  18. Chou SM, Gilbert EF, Chun RWM et al. (1990) Infantile olivopontocerebellar atrophy with spinal muscular atrophy (infantile OPCA+SMA). ClinNeuropathol 9: 21–32

    CAS  Google Scholar 

  19. Constantinidis J, Richard J, Tissot R (1974) Pick’s disease. Histological and clinical correlations. Eur Neurol 11: 08–217

    Google Scholar 

  20. Currier RD (1984) A classification for ataxia. In: Duvoisin RC, Plaitakis A (eds) The olivopontocerebellar atrophies. Raven, New York, pp 1–4

    Google Scholar 

  21. Dale GE, Probst A, Luthert P et al. (1992) Relationship between Lewy bodies and pale bodies in Parkinson’s disease. Acta Neuropathol 83: 525–529

    PubMed  CAS  Google Scholar 

  22. Deng HX, Hentati A, Trainer JA et al. (1993) Amyotrophic lateral sclerosis and structural defects in CU,Zn superoxide dismutase. Nature 261: 1047–1051

    CAS  Google Scholar 

  23. Dickson DW, Wertkin A, Kress Y, Ksiezak-Reding H, Yen SH (1990) Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects. Lab Invest 63: 87–99

    PubMed  CAS  Google Scholar 

  24. Duclos F, Boschert U, Sirugo G et al. (1993) Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. Proc Nat! Acad Sci USA 90: 109–113

    PubMed  CAS  Google Scholar 

  25. Eiber J, Weber K, Schöls L (1992) Kardiomyopathie bei Friedreich- Ataxie. Dtsch Med Wschr 117: 432–436

    PubMed  CAS  Google Scholar 

  26. Farrant M, Cull-Candy S (1993) GABA receptors, granule cells and genes. Nature 361: 302–303

    PubMed  CAS  Google Scholar 

  27. Fearnley JM, Lees AJ (1990) Striatonigral degeneration. A clinicopathological study. Brain 113: 1823–1842

    Google Scholar 

  28. Ferrante RJ, Kowall NW, Cipolloni PB, Storey E, Beal MF (1993) Excitotoxin lesions in primates as a model for Huntington’s disease: histopathologic and neurochemical characterization. Exp Neurol 119: 46–71

    PubMed  CAS  Google Scholar 

  29. Finocchiaro G, Baio G, Micossi P, Pozza G, di Donato S (1988) Glucose metabolism alterations in Friedreich’s ataxia. Neurology 38: 1292–1296

    PubMed  CAS  Google Scholar 

  30. Forno LS, Langston JW, DeLanney LE, Irwin I (1988) An electron microscopic study of MPTP-induced inclusion bodies in an old monkey. Brain Res 448: 150–157

    PubMed  CAS  Google Scholar 

  31. Gibb WRG (1989) Neuropathology in movement disorders. J Neurol Neurosurg Psychiatry [SuppI54]: 55–67

    Google Scholar 

  32. Gibb WRG, Lees AJ (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease. J Neurol Neurosurg Psychiatry 51: 745–752

    PubMed  CAS  Google Scholar 

  33. Golbe LL, Lazzarini AM, Schwarz KO et al. (1993) Autosomal dominant parkinsonism with benign course and typical Lewybody pathology. Neurology 43: 2222–2227

    PubMed  CAS  Google Scholar 

  34. Hansen LA, Masliah E, Galasko D, Terry RD (1993) Plaqueonly Alzheimer disease is usually the Lewy body variant, and vice versa. J Neuropathol Exp Neurol 52: 648–654

    PubMed  CAS  Google Scholar 

  35. Hardie RJ, Pullon HWH, Harding AE et al. (1991) Neuroacanthocytosis. A clinical, haematological and pathological study of 19 cases. Brain 114: 13–49

    PubMed  Google Scholar 

  36. Hauw JJ, Verny M, Delaere P et al. (1990) Constant neurofibrillary changes in the neo cortex in progressive supranuclear palsy. Basic differences with Alzheimer’s disease and aging. Neurosci Lett 119: 182–186

    PubMed  CAS  Google Scholar 

  37. Hedreen JC, Peyser CE, Folstein SE, Ross CA (1991) Neuronal loss in layers V and VI of cerebral cortex in Huntington’s disease. Neurosci Lett 133: 257–261

    PubMed  CAS  Google Scholar 

  38. Horoupian DS, Dickson DW (1991) Striatonigral degeneration, olivopontocerebellar atrophy and “atypical” Pick disease. Acta Neuropathol 81: 287–295

    PubMed  CAS  Google Scholar 

  39. Hudson AJ (1991) Amyotrophic lateral sclerosis/parkinsonism/dementia: clinicopathological correlations relevant to Guamanian ALS/PD. Can J Neurol Sci 18: 387–389

    PubMed  CAS  Google Scholar 

  40. Hulette CM, Crain BJ (1992) Lobar atrophy without Pick bodies. Clin Neuropathol 11: 151–156

    PubMed  CAS  Google Scholar 

  41. Ince P, Irving D, MacArthur F, Perry RH (1991) Quantitative neuropathological study of Alzheimer-type pathology in the hippocampus: comparison of senile dementia of Alzheimer type, senile dementia of Lewy body type, Parkinson’s disease and non-demented elderly controls. J Neurol Sci 106: 142–152

    PubMed  CAS  Google Scholar 

  42. Jellinger K (1986) (Exogenous) striatal necrosis. In: Vinken PJ, Bruyn GW, Klawans HL (eds) Handbook of clinical neurology. vol 5. Elsevier. Amsterdam, pp 499–518

    Google Scholar 

  43. Jellinger K (1986) Pallidal, pallidonigral and pallidoluysionigral degenerations including association with thalamic and dentate degenerations. In: Vinken PJ, Bruyn GW, Klawans HL (eds) Handbook of clinical neurology, vol 5. Elsevier. Amsterdam. pp 445–463

    Google Scholar 

  44. Jellinger K (1989) Pathology of Parkinson’s syndrome. In: Calne DB. (ed) Handbook of experimental pharmacology, vol 88, Springer. Berlin Heidelberg New York Tokio. pp 47–112

    Google Scholar 

  45. Jellinger K (1991) Pathology of Parkinson’s disease. Changes other than the nigrostriatal pathway. Mol Chem Neuropathol 14: 153–197

    PubMed  CAS  Google Scholar 

  46. Jellinger K, Bancher C (1992) Neuropathology. In: Litvan I, Agid Y (eds) Progressive supranuclear palsy. Clinical and research approaches. Oxford Univ Press, New York, pp 44–88

    Google Scholar 

  47. Jellinger K, Braak H. Braak E. Fischer P (1991) Alzheimer lesions in the entorhinal region and isocortex in Parkinson’s and Alzheimer’s diseases. NY Acad Sci 640: 203–209

    CAS  Google Scholar 

  48. Jellinger KA, Lantos PL, Mehraein P (1993) Pathological assessment of movement disorders: requirements for documentation in brain banks. J Neural Transm [SuppI39]: 173–184

    Google Scholar 

  49. Jellingcr K, Paulus W. Grundke-Iqbal L. Riederer P, Youdim MBH (1990) Brain iron and ferritin in Parkinson’s and Alzheimer’s diseases. J Neural Transm (P-D Sect) 2: 327–340

    Google Scholar 

  50. Jellinger K, Tarnowska-Dziduszko E (1971) Die ZNS-Veranderungen bei den olivo-ponto-zerebellaren Atrophien. Z Neurol 199: 192–214

    PubMed  CAS  Google Scholar 

  51. Jentsch S (1992) The ubiquitin-conjugation system. Ann Rev Genet 26: 179–207

    PubMed  CAS  Google Scholar 

  52. Kato S. Hirano A (1990) Ubiquitin and phosphorylated neurofilament epitopes in ballooned neurons of the extraocular muscle nuclei in a case of Werdnig-Hoffmann disease. Acta Neuropathol 80: 334–337

    PubMed  CAS  Google Scholar 

  53. Kato S. Hirano A. Umahara T et al. (1992) Comparative immunohistochemical study on the expression of a B crystallin, ubiquitin and stress-response protein 27 in ballooned neurons in various disorders. Neuropathol Appl Neurobiol 18: 335–340

    PubMed  Google Scholar 

  54. Kato S, Nakamura H (1990) Presence of two different fibril subtypes in the Pick body: an immunoelectron microscopic study. Acta Neuropathol 8l: 125–129

    Google Scholar 

  55. Kato S, Nakamura H, Hirano A et al. (1991) Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy). Acta Neuropathol 82: 481–493

    Google Scholar 

  56. Kawamata T. Akiyama H, Yamada T, McGeer PL (1992) Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am J Pathol 140: 691–707

    PubMed  CAS  Google Scholar 

  57. Kisby GE, Ellison M. Spencer PS (1992) Content of the neurotoxins cycasin (mcthylazoxymethanol β-D-glucoside) and BMAA (β-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros. Neurology 42: 1336–1340

    PubMed  CAS  Google Scholar 

  58. Kish SJ, Robitaille Y. EI-Awar M et al. (1991) Brain amino acid reductions in one family with chromosome 6 p-linked dominantly inherited olivopontocerehellar atrophy. Ann Neurol 30: 780–784

    PubMed  CAS  Google Scholar 

  59. Klemm E, Tackmann W (1991) Familiare spastische Spinalparalyse. Klinisches Spektrum und differentialdiagnostische Erwagungen. Fortschr Neurol Psychiatr 59: 176–182

    PubMed  CAS  Google Scholar 

  60. Klockgether T. Petersen D, Grodd W. Dichgans J (1991) Early onset cerebellar ataxia with retained tendon reflexes. Clinical. electro physiological and MRI observations in comparison with Friedreich’s ataxia. Brain 114: 1559–1573

    PubMed  Google Scholar 

  61. Klockgether T, Schroth G, Diener HE, Dichgans J (1990) Idiopathic cerebellar ataxia of late onset: natural history and MRI morphology. J Neurol Neurosurg Psychiatry 53: 297–305

    PubMed  CAS  Google Scholar 

  62. Kobayashi K, Miyazu K, Katsukawa K, et al. (1992) Cytoskeletal protein ahnormalities in patients with olivopontocerebellar atrophy. An immunocytochemical and Gallyas silver impregnation study. Neuropathol Appl Neurohiol 18: 237–249

    CAS  Google Scholar 

  63. Koeppen AH (1991) The Purkinjc cell and its afferents in human hereditary ataxia. J Neuropathol Exp Neurol 50: 505–514

    PubMed  CAS  Google Scholar 

  64. Konigsmark BW, Weiner LP (1970) The olivopontocerebellar atrophies: a review. Medicine 49: 227–241

    PubMed  CAS  Google Scholar 

  65. Kosaka K (1990) Diffuse Lewy body disease in Japan. J Neurol 237:197–204

    PubMed  CAS  Google Scholar 

  66. Kosaka K. Ikeda K. Kobayashi K. Mehraein P (1991) Striatopallidonigral degeneration in Pick’s disease: a clinicopathological study of 41 cases. J Neuro1 238: 151–160

    Google Scholar 

  67. Kume A, Takahashi A, Hashizume Y, Asai J (1991) A histometrical and comparative study on Purkinje cell loss and olivary nucleus cell loss in multiple system atrophy. J Neurol Sci 101: 178–186

    PubMed  CAS  Google Scholar 

  68. Kushner PD, Stephenson DT, Wright S (1991) Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain. J Neuropathol Exp Neurol 50: 263–277

    PubMed  CAS  Google Scholar 

  69. La Spada AR, Wilson EM, Lubahn DB, Harding AE, Fischbeck KH (1991) Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352: 77–79

    PubMed  Google Scholar 

  70. Leigh PN, Withwell H, Garofalo O, et al. (1991) Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain 114: 775–788

    PubMed  Google Scholar 

  71. Lowe J, Mayer RJ, Landon M (1993) Ubi quit in in neurodegenerative diseases. Brain Pat hoi 3: 55–65

    CAS  Google Scholar 

  72. Mann DMA, Oliver R, Snowden JS (1993) The topographic distribution of brain atrophy in Huntington’s disease and progressive supranuclear palsy. Acta Neuropathol 85: 553–559

    PubMed  CAS  Google Scholar 

  73. Mann DMA. South PW, Snowden JS, Neary D (1993) Dementia of frontal lobe type: neuropathology and immunohistochemistry. J Neurol Neurosurg Psychiatry 56: 605–614

    PubMed  CAS  Google Scholar 

  74. Matsumoto S, Kusaka H, Murakami N et al. (1992) Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: an immunocytochemical and ultrastructural study. Acta Neuropathol 83: 579–583

    PubMed  CAS  Google Scholar 

  75. Melki J, Sheth P, Abdelhak S et al. (1990) Mapping of acute (type I) spinal muscular atrophy to chromosome 5 q 12-q 14. Lancet 336: 271–273

    PubMed  CAS  Google Scholar 

  76. Mizusawa H, Nakamura H, Wakayama I, Yen SHC, Hirano A (1991) Skein-like inclusions in the anterior horn cells in motor neuron disease. J Neurol Sci 105: 14–21

    PubMed  CAS  Google Scholar 

  77. Mizutani T, Aki M, Shiozawa R, et al. (1990) Dvelopment of ophthalmoplegia in amyotrophic lateral sclerosis during longterm use of respirators. J Neurol Sci 99: 311–319

    PubMed  CAS  Google Scholar 

  78. Monaco S, Nardelli E, Moretto G, Cavallaro T, Rizzuto N (1988) Cytoskeletal pathology in ataxia-telangiectasia. Clin Neuropathol 7: 44–46

    PubMed  CAS  Google Scholar 

  79. Murayama S, Bouldin TW, Suzuki K (1992) Pathological study of corticospinal-tract degeneration in Friedreich’s ataxia. Neuropathol Appl Neurobiol 18: 81–86

    PubMed  CAS  Google Scholar 

  80. Murayama S, Bouldin TW, Suzuki K (1992) Immunocytochemical and ultrastructural studies of upper motor neurons in amyotrophic lateral sclerosis. Acta Neuropathol 83: 518–524

    PubMed  CAS  Google Scholar 

  81. Murayama S, Mori H, Ihara Y, Tomonaga M (1990) Immunocytochemical and ultrastructural studies of Pick’s disease. Ann Neurol 27: 394–405

    PubMed  CAS  Google Scholar 

  82. Myers RH, Vonsattel JP, Paskevich PA, et al. (1991) Decreased neuronal and increased oligodendroglial densities in Huntington’s disease caudate nucleus. J Neuropathol Exp Neurol 50: 729–742

    PubMed  CAS  Google Scholar 

  83. Nakano I, Iwatsubo T, Hashizume Y, Mizutani T (1993) Bunina bodies in neurons of the medullary reticular formation in amyotrophic lateral sclerosis. Acta Neuropathol 85: 471–474

    PubMed  CAS  Google Scholar 

  84. Nishimura M, Namba Y, Ikeda K, Oda M (1992) Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy. Neurosci Lett 143: 35–38

    PubMed  CAS  Google Scholar 

  85. Olanow CW (1992) An introduction to the free radical hypothesis in Parkinson’s disease. Ann Neurol 32: S2-S9

    PubMed  CAS  Google Scholar 

  86. Oppenheimer DR (1979) Brain lesions in Friedreich’s ataxia. Can J Neurol Sci 6: 173–176

    PubMed  CAS  Google Scholar 

  87. Oppenheimer DR (1988) Neuropathology of autonomic failure. In: Bannister R. (ed) Autonomic failure, 2nd ed. Oxford Univ Press. Oxford, pp 451–463

    Google Scholar 

  88. Papp MI, Lantos PL (1992) Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy. J Neurol Sci 107: 172–182

    PubMed  CAS  Google Scholar 

  89. Paulus W, Jellinger K (1991) The neuropathologic basis of different clinical subgroups of Parkinson’s disease. J Neuropathol Exp Neurol 50: 743–755

    PubMed  CAS  Google Scholar 

  90. Paulus W, Selim M (1990) Corticonigral degeneration with neuronal achromasia and basal neurofibrillary tangles. Acta Neuropathol 81: 89–94

    PubMed  CAS  Google Scholar 

  91. Pfeiffer RF, McComb RD (1990) Dentatorubro-pallidoluysian atrophy of the myoclonus epilepsy type with posterior column degeneration. Movement Disord 5: 134–138

    PubMed  CAS  Google Scholar 

  92. Pittella JEH, Nogueira AMMF (1990) Pontoneocerebellar hypoplasia: report of a case in a newborn and review of the literature. Clin Neuropathol 9: 33–38

    PubMed  CAS  Google Scholar 

  93. Pollanen MS, Dickson DW, Bergeron C (1993) Pathology and biology of the Lewy body. J Neuropathol Exp Neurol 52: 183–191

    PubMed  CAS  Google Scholar 

  94. Pringle CE, Hudson AJ, Munoz DG et al. (1992) Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria. Brain 115: 495–520

    PubMed  Google Scholar 

  95. Rajput AH, Vitti RJ, Sudhakar S, Rozdilsky B (1989) Parkinsonism and neurofibrillary tangle pathology in pigmented nuclei. Ann Neurol 25: 602–606

    PubMed  CAS  Google Scholar 

  96. Rosenberg RN (1992) Machado-Joseph disease: an autosomal dominant motor system degeneration. Movement Disord 7: 193–203

    PubMed  CAS  Google Scholar 

  97. Rosenberg RN (1993) An introduction to the molecular genetics of neurological disease. Arch Neurol 50: 1123–1128

    PubMed  CAS  Google Scholar 

  98. Rothstein JD, Martin U, Kuncl RW (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 326: 1464–1468

    PubMed  CAS  Google Scholar 

  99. Sasaki S, Maruyama S (1991) Immunocytochemical and ultrastructural studies of hyaline inclusions in sporadic motor neuron disease. Acta Neuropathol 82: 295–301

    PubMed  CAS  Google Scholar 

  100. Shishikura K, Hara M, Sasaki Y, Misugi K (1983) A neuropathologic study of Werdnig-Hoffmann disease with special reference to the thalamus and posterior roots. Acta Neuropathol 60:99–106

    PubMed  CAS  Google Scholar 

  101. Snowden IS, Neary D, Mann DMA, Goulding PI, Testa HI (1992) Progressive language disorder due to lobar atrophy. Ann NeuroI 31:174–183

    CAS  Google Scholar 

  102. Tanner CM, Langston IW (1990) Do environmental toxins cause Parkinson’s disease? A critical review. Neurol 40 [SuppI3]: 17–30

    Google Scholar 

  103. Thach WT, Goodkin HP, Keating JG (1992) The cerebellum and the adaptive coordination of movement. Ann Rev Neurosci 15: 403–442

    PubMed  CAS  Google Scholar 

  104. The Huntington’s Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell 72: 971–983

    Google Scholar 

  105. Tokuda T, Ikeda S, Yanagisawa N, Ihara Y, Glenner GG (1991) Re-examination of ex-boxers’ brains using immunohistochemistry with antibodies to amyloidβ-protein and t-protein. Acta Neuropathol 82: 280–285

    PubMed  CAS  Google Scholar 

  106. Troost D, Sillevis Smitt PAE, de Jong JMBV, Swaab DF (1992) Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis. Acta Neuropathol 84: 664--673

    PubMed  CAS  Google Scholar 

  107. Vonsattel JP, Myers RH, Stevens TJ et al. (1985) Neuropathological classification of Huntington’s disease. J Neuropathol Exp NeuroI 44:559–577

    CAS  Google Scholar 

  108. Wallace DC (1992) Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 256: 628--632

    PubMed  CAS  Google Scholar 

  109. Warzok R, Wattig B, Schwesinger G, Schneeweiss H, Heydenreich F (1990) Zur nosologischen Stellung der hereditären motorischen und sensiblen Neuropathien (HMSN, Charcot-MarieTooth- Krankheit, neurale Muskelatrophie). Zentralbl Allg Pathol 136: 549–562

    PubMed  CAS  Google Scholar 

  110. Wightman G, Anderson VER, Martin J, et al. (1992) Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia. Neurosci Lett 139: 269–274

    PubMed  CAS  Google Scholar 

  111. Wszolek ZK, Pfeiffer RF, Bhatt MH et al. (1992) Rapidly progressive autosomal dominant Parkinsonism and dementia with pallido-ponto-nigral degeneration. Ann Neurol 32: 312–320

    PubMed  CAS  Google Scholar 

  112. Zerres K (1989) Klassifikation und Genetik spinaler Muskel atrophien. Thieme, Stuttgart New York

    Google Scholar 

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Paulus, W. (1995). Systematrophien. In: Remmele, W., Peiffer, J., Schröder, J.M. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85179-7_13

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