Cancer of the Esophagus and Stomach
From an epidemiologic point of view, cancer of the esophagus is interesting because of the 30-fold variation in incidence in different parts of the world — from high-risk areas such as China to low-risk areas in the United States. Because of frequent extensive submucosal spread up and down the esophagus at diagnosis, wide surgical resections are necessary to avoid leaving residual disease at the resection margins. Diagnosis is often late because the main symptom, dysphagia, does not occur until the tumor grows large enough to obstruct.
KeywordsAdenocarcinoma Barium Doxorubicin Methotrexate Smoke
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