Neurotoxic Agents Interacting with the Muscarinic Acetylcholine Receptor

  • J. Järv
Part of the Springer Study Edition book series (volume 102)


The neurotransmitter acetylcholine (ACh) exerts two types of effects, differing, in their location and in the nature of the associated physiological responses and pharmacology (Dale 1914). These observations have led to the definition of two major types of ACh receptors, specified as nicotinic and muscarinic because their characteristic responses can be evoked by nicotine and muscarine, respectively (Michaelson and Zeimal 1973).


Muscarinic Receptor Muscarinic Acetylcholine Receptor Muscarinic Agonist Muscarinic Antagonist Neurotoxic Agent 
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  • J. Järv

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