Abstract
Liver resection is the most effective therapy for hepatocellular carcinoma (HCC), but associated chronic liver diseases such as cirrhosis of the liver often limit its use. We started to use portal vein embolization (PVE) with an adhesive mixture of fibrin as an adjuvant therapy to improve the outcome of surgical treatment. We investigated the clinical course after PVE and operative specimens in which PVE had been done. PVE strengthened the anticancer effect of transcatheter arterial embolization (TAE). PVE causes regeneration of the nonembolized lobe and atrophy of the embolized lobe, which extends the surgical indications for patients with HCC and makes surgery safer if the patients have cirrhosis. Nonrecurrence survival rates in the patients in whom preoperative PVE had been done tended to be better than in the patients without this treatment. PVE seems to be useful as preparation for surgery and as one therapy for unresectable HCC, usually to be done together with other treatments.
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© 1994 Springer-Verlag Berlin Heidelberg
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Kubo, S., Kinoshita, H., Hirohashi, K. (1994). Preoperative Portal Vein Embolization with Fibrin Sealant for Hepatocellular Carcinoma. In: Schlag, G., Waclawiczek, HW., Daum, R. (eds) Fibrin Sealing in Surgical and Nonsurgical Fields. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85101-8_3
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DOI: https://doi.org/10.1007/978-3-642-85101-8_3
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