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Management of Chronic Idiopathic Thrombocytopenia (Werlhof’s Disease) by Partial Splenic Resection — An Alternative to Splenectomy in Childhood?

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Fibrin Sealing in Surgical and Nonsurgical Fields

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Abstract

Medical management of chronic idiopathic thrombocytopenia (ITP) in childhood often fails [20, 26], which is why splenectomy is the recommended method of choice in these cases. However, surgery may not guarantee permanent therapeutic effects either: removal of the spleen may be accompanied by an increased risk of postsplenectomy infections (overwhelming post-splenectomy infection, OPSI syndrome). For these reasons we carried out partial splenic resection in nine children with chronic ITP. The aim of this procedure was to influence the course of chronic ITP by saving the immunological competence of children. Results from a clinical, hematological, and immunological point of view are discussed.

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Authors
  1. U. Specht
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  2. F. Kirchmair
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  3. P. Degenhardt
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  4. H. Mau
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  5. S. Jahn
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Editor information

Editors and Affiliations

  1. Ludwig-Boltzmann-Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, 1200, Wien, Austria

    Günther Schlag

  2. 1st Surgery Department, Landeskrankenanstalten Salzburg, Müllner Hauptstraße 48, 5020, Salzburg, Austria

    H.-W. Waclawiczek

  3. Clinic of Surgery Dept. for Pediatric Surgery, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    R. Daum

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© 1994 Springer-Verlag Berlin Heidelberg

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Specht, U., Kirchmair, F., Degenhardt, P., Mau, H., Jahn, S. (1994). Management of Chronic Idiopathic Thrombocytopenia (Werlhof’s Disease) by Partial Splenic Resection — An Alternative to Splenectomy in Childhood?. In: Schlag, G., Waclawiczek, HW., Daum, R. (eds) Fibrin Sealing in Surgical and Nonsurgical Fields. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85101-8_25

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  • DOI: https://doi.org/10.1007/978-3-642-85101-8_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57742-3

  • Online ISBN: 978-3-642-85101-8

  • eBook Packages: Springer Book Archive

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