Lymphorrhea and Seroma Prevention by Means of Fibrin Glue in Breast and Head and Neck Cancer
Bleeding and lymphorrhea are very frequent side effects in breast cancer (BC) and in head and neck cancer (HNC). They are related to wide muscular resection and/or lymphatic dissection which can delay wound healing in tissue repair. In order to reduce such side effects, between January 1989 and February 1992 two separate groups of patients with BC and HNC underwent intraoperative topical fibrin glue application. In both groups, a reduction in lymphorrhea, wound infection, and, consequently, length of hospitalization was observed as compared to previous experience.
KeywordsBreast Cancer Fibrin Glue Fibrin Sealant Radical Neck Dissection Delay Wound Healing
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- 1.Giardino R, Fini M (1990) I collanti in chirurgia. Proc SIATEC VI: 495–503Google Scholar
- 3.Moresco L (1989) Impiego del Tissucol nella chirurgia del cancro mammario. Proc SIATEC V: 567–569Google Scholar
- 4.Moresco L, Scala M, Canavese G, Bertoglio S, Cafiero F (1988) Il collante biologico in chirurgia oncologica. Proc SICO XII: 599–603Google Scholar
- 6.Redl H, Schlag G, Dinges HP (1985) The use and biocompatibility of a human fibrin sealant for hemostasis and tissue sealing. Biocomp Tissue Tissue Analog 1: 136–157Google Scholar