Lymphorrhea and Seroma Prevention by Means of Fibrin Glue in Breast and Head and Neck Cancer
Bleeding and lymphorrhea are very frequent side effects in breast cancer (BC) and in head and neck cancer (HNC). They are related to wide muscular resection and/or lymphatic dissection which can delay wound healing in tissue repair. In order to reduce such side effects, between January 1989 and February 1992 two separate groups of patients with BC and HNC underwent intraoperative topical fibrin glue application. In both groups, a reduction in lymphorrhea, wound infection, and, consequently, length of hospitalization was observed as compared to previous experience.
KeywordsMigration Syringe Thrombin Fibrinogen
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