Advertisement

Comparison of Myosin in Denervated and Immobilized Muscles

  • A. Jakubiec-Puka
  • J. Szczepanowska
Conference paper

Abstract

Striated muscles differ in respect to velocity, power of contraction and resistence to fatigue. The striated muscle is a very plastic and adaptable tissue [8]; transformation of fibre types, muscle hypertrophy or atrophy can appear within a short time [3, 4, 6]. Alterations occur as a result of functional or anatomical demands, hormonal influence etc. Both denervation and immobilization bring about muscle atrophy and diminishing of the contractile apparatus (references in [3, 4, 7, 9]), but differences between the effect of inactivity and that of lack of innervation are not fully understood. The type-dependent differences in muscle reaction are also unclear. All these issues are of practical importance.

Keywords

Actin Filament Myosin Heavy Chain Slow Muscle Fast Muscle Contractile Apparatus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Carraro U, Catani C., (1983) A sensitive SDS-PAGE method separating myosin heavy chain isoforms of rat skeletal muscles reveals the heterogeneous nature of the embryonic myosin. Biochem Biophys Res Commun 116: 793–802PubMedCrossRefGoogle Scholar
  2. 2.
    Carraro U, Catani C, Degani A, Rizzi C., (1990) Myosin expression in denervated fast- and slow-twitch muscles: fiber modulation and substitution. In: Pette D., (ed) The dynamic state of muscle fibres. De Gruyter, Berlin, pp 247–261Google Scholar
  3. 3.
    Jakubiec-Puka A, Kulesza-Lipka D, Krajewski K., (1981) The contractile apparatus of striated muscle in the course of atrophy and regeneration. I. Myosin and actin filaments in the denervated rat soleus. Cell Tissue Res 220: 651–663Google Scholar
  4. 4.
    Jakubiec-Puka A, Kordowska J, Catani C, Carraro U., (1990) Myosin heavy chain isoform composition in striated muscle after denervation and self-reinnervation. Eur J Biochem 193: 623–628PubMedCrossRefGoogle Scholar
  5. 5.
    Jakubiec-Puka A, Carraro U., (1991) Remodelling of the contractile apparatus of striated muscle stimulated electrically in a shortened position. J Anat 178: 83–100PubMedGoogle Scholar
  6. 6.
    Jakubiec-Puka A, Catani C, Carraro U., (1992) Myosin heavy chain composition in striated muscle after tenotomy. Biochem J 282: 237–242PubMedGoogle Scholar
  7. 7.
    Jakubiec-Puka A., (1992) Changes in myosin and actin filaments in fast skeletal muscle after denervation and self-reinnervation. Comp Biochem Physiol 102 A: 93–98Google Scholar
  8. 8.
    Pette D, Staron RS., (1990) Cellular and molecular diversities of mammalian skeletal muscle fibers. Rev Physiol Biochem Pharmacol 116: 1–76PubMedGoogle Scholar
  9. 9.
    Szczepanowska J, Jakubiec-Puka A., (1992) Myosin heavy chains in striated muscle after immobilization. Basic Appl Myol 2: 97–105Google Scholar

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • A. Jakubiec-Puka
    • 1
  • J. Szczepanowska
    • 1
  1. 1.Department of Cell BiochemistryNencki Institute of Experimental BiologyWarsawPoland

Personalised recommendations