Hereditary Gastrointestinal Polyposis Syndromes

  • M. Ponz de Leon
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 136)


Familial gastrointestinal polyposis includes various syndromes with common features of numerous adenomatous polyps in the large bowel and a well- defined pattern of genetic transmission. The occurrence of other clinical manifestations will determine the appearance of the specific phenotypes, which have been tentatively classified in Table 1. This, however, is not a simple task, since there is still much debate concerning whether some of these syndromes should be considered separate nosologic entities or part of the spectrum of alterations associated with a single disease. While it is unlikely that further clinical studies will provide new insights into the classification of familial polyposis, this question might be answered in the near future by the biomolecular characterization of the underlying genetic defects.


Familial Adenomatous Polyposis Desmoid Tumor Juvenile Polyposis Supernumerary Tooth Familial Polyposis Coli 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • M. Ponz de Leon
    • 1
  1. 1.Istituto di Patologia Medica PoliclinicoUniversità degli Studi di ModenaModenaItaly

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