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Hereditary and Familial Colorectal Cancer

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Book cover Familial and Hereditary Tumors

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 136))

Abstract

Colorectal cancer is a major cause of death in Western countries and one of the neoplasms in which the contribution of heritable factors has been investigated in more detail, in terms of both genetic epidemiology and molecular biology.

Large bowel cancer has complex, multifactorial etiologic factors, each of which play a major or minor role, through specific mechanisms, in the overall prolonged process leading to clinically overt cancer. Some factors may be directly causative, others may enhance or promote, and still others may be protective or inhibiting. (J. H. Weisburger and E. L. Wynder 1987)

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  1. Istituto di Patologia Medica Policlinico, Università degli Studi di Modena, Via del Pozzo, 71, 41100, Modena, Italy

    Prof. Dr. M. Ponz de Leon

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de Leon, M.P. (1994). Hereditary and Familial Colorectal Cancer. In: Familial and Hereditary Tumors. Recent Results in Cancer Research, vol 136. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85076-9_15

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