Epidemiological Aspects of Hypercalcemia of Malignancy
Hypercalcemia can be caused by many disorders, but is most commonly due to primary hyperparathyroidism and to malignant disease. Together, these account for more than 90% of all cases. Many patients with primary hyperparathyroidism are asymptomatic and ambulant when hypercalcemia is first recognized by routine measurement of serum calcium levels. However, the incidence of hypercalcemia of cancer, which has been estimated to be about 150 new cases per million persons per year, is not as high as the annual incidence rate of primary hyperparathyroidism (approximately 250 new cases per year) (Burkhardt and Kistler 1981; Heath et al. 1980; Mundy et al. 1980, 1984).
KeywordsLymphoma Estrogen Oncol Sarcoma Flare
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