Catabolism — Potential for Amelioration by Growth Factors

  • G. D. Yarwood
  • J. H. Coakley
  • R. J. M. Ross
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine 1994 book series (YEARBOOK, volume 1994)


Trauma, sepsis and surgery are characterized by the development of a catabolic state with net breakdown of protein, carbohydrate and fat to meet increased energy demands and to supply the metabolic fuels required for gluconeogenesis and acute phase protein synthesis. Prolonged or more severe metabolic stress can overwhelm the ability of the body to supply these endogenous substrates; such self-destructive autocannibalism [1] results in muscle wasting, an impaired immune response and prolonged hospital admission [2].


Cecal Ligation Caecal Ligation Acute Phase Protein Synthesis Biosynthetic Human Growth Hormone Severe Metabolic Stress 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • G. D. Yarwood
  • J. H. Coakley
  • R. J. M. Ross

There are no affiliations available

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