Structural and Environmental Studies of the Vitamin E (α-Tocopheroxyl) Radical Using Time-Resolved Resonance-Raman Spectroscopy

  • A. W. Parker
  • R. H. Bisby
Conference paper
Part of the Springer Proceedings in Physics book series (SPPHY, volume 74)


The time-resolved resonance Raman spectrum of the vitamin E free radical, α-tocopheroxyl, has been measured. The spectrum is similar to that obtained for 4-methoxyphenoxyl, i.e. consisting of two intense bands at ca. 1500 and 1595 cm−1, assigned to the C=C (v 8a) and C-O (v 7a) stretches respectively. This indicates that the vitamin E free radical is stabilised by electron delocalisation involving the chromanol ring oxygen. The ratio of these two bands increases with increase in solvent polarity. This has been used to determine the position of the α-tocopherol radical within lipid bilayer membranes.


Probe Laser Lipid Bilayer Membrane Transient Absorption Spectrum Laser Flash Photolysis Resonance Raman Spectrum 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • A. W. Parker
    • 1
  • R. H. Bisby
    • 2
  1. 1.Rutherford Appleton LaboratorySERCChilton, Didcot, OxonUK
  2. 2.Department of Biological SciencesUniversity of SalfordSalfordUK

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