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Epidermal Growth Factor Receptor Gene and Its Transcripts in Glioblastomas

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Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 135))

Abstract

The astrocytic variants of the gliomas, comprising astrocytoma, anaplastic astrocytoma, and glioblastoma, form the most common group of these tumours in adults (Walker et al. 1985) and together account for approximately 50% of primary intracranial tumours. Glioblastomas make up almost half of these and are unfortunately the most malignant tumours of the series (Mahaley et al. 1989). Thus, due to their frequency the astrocytic group of gliomas has received most attention, with the glioblastomas being particularly well studied, due to their abundance and biological aggressiveness.

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Author information

Authors and Affiliations

  1. Division of Neuropathology, Department of Pathology, Sahlgrenska Hospital, 41345, Gothenburg, Sweden

    V. P. Collins

  2. Ludwig Institute for Cancer Research, Stockholm Branch, Karolinska Hospital, S-17176, Stockholm, Sweden

    V. P. Collins

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  1. V. P. Collins
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Editor information

Editors and Affiliations

  1. Institut für Neuropathologie, Universitätskliniken Bonn, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    O. D. Wiestler

  2. Neurologische Universitätsklinik, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    U. Schlegel  & J. Schramm  & 

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© 1994 Springer-Verlag Berlin Heidelberg

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Collins, V.P. (1994). Epidermal Growth Factor Receptor Gene and Its Transcripts in Glioblastomas. In: Wiestler, O.D., Schlegel, U., Schramm, J. (eds) Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors. Recent Results in Cancer Research, vol 135. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85039-4_3

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  • DOI: https://doi.org/10.1007/978-3-642-85039-4_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85041-7

  • Online ISBN: 978-3-642-85039-4

  • eBook Packages: Springer Book Archive

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